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Corticosteroids Not Superior to Placebo for Add-On Treatment of Bacterial Keratitis

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Adjunctive corticosteroids not superior to placebo, while adjunctive corneal cross-linking associated with increased scar size

Urgent Care Visits Often Linked to Inappropriate Prescribing

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Overall, 12.4, 9.1, and 1.3 percent of urgent care visits led to antibiotic, glucocorticoid, and opioid prescription fills, respectively

Hyperbaric Therapy + Corticosteroid Combo Aids Sudden Sensorineural Hearing Loss

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Early initiation within 12.5 days of hearing loss onset tied to better hearing outcomes

Severe Exacerbations Down With As-Needed Albuterol-Budesonide for Mild Asthma

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Severe exacerbation occurred in fewer patients receiving albuterol-budesonide versus those receiving albuterol only

Methotrexate Noninferior to Prednisone in Pulmonary Sarcoidosis

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Methotrexate noninferior to prednisone with regard to change from baseline to week 24 in percentage of predicted forced vital capacity

Midafternoon Dosing Improves Lung Function in Atopic Asthma

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Improvement seen in nocturnal lung function and overnight suppression of blood eosinophil counts

Adverse Outcomes Increased With Long-Term Inhaled Corticosteroids in COPD

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Significantly greater composite adverse outcome rates seen for long- versus short-term inhaled corticosteroid use for prevalent, inception cohorts

IBD Activity May Increase Risk for Clostridioides Difficile Infection

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CDI episodes frequently preceded by corticosteroid usage; risk was increased with recently diagnosed IBD

Pericarditis Recurrence Occurs in About 20 Percent of Patients With Lupus

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Factors associated with recurrence include younger age, prednisone treatment, active systemic lupus erythematosus, time since initial episode

Epidural Steroid Injections Reviewed for Radicular Pain, Spinal Stenosis

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Some evidence seen for ESIs reducing pain and disability in cervical and lumbar radiculopathies and possibly in lumbar spinal stenosis