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A consensus statement for the use of hematopoietic stem cell transplantation in the treatment of multiple myeloma has been developed by Mayo Clinic physicians; the recommendations were published in the March issue of Bone Marrow Transplantation.

Recommendations Issued for HSCT in Multiple Myeloma

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Autologous stem cell transplant remains essential component of MM therapy in eligible patients
For children with B-cell precursor acute lymphoblastic leukemia with late bone marrow relapse

Favorable Outcomes Seen in Long Term for ALLR3 Trial

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Findings for risk-stratified tx in B-cell precursor acute lymphoblastic leukemia, late bone marrow relapse
In only the second known case worldwide

Second Man HIV-Free After Stem Cell Transplant

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Donor had double copy of gene mutation that confers natural resistance to HIV
Autologous stem cell transplantation may be beneficial for some patients with nodal peripheral T-cell lymphoma in the first complete remission

Autologous Stem Cell Transplant May Aid Some With Nodal PTCL

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Prospective cohort study suggests benefit of ASCT for some with nodal peripheral T-cell lymphoma
For some children with hypodiploid acute lymphoblastic leukemia

Addition of BMT Not Indicated in Some With Peds Hypodiploid ALL

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Bone marrow transplant not beneficial if no minimal residual dz after remission induction tx
For patients with relapsing-remitting multiple sclerosis

Stem Cell Transplant Slows Progression of Multiple Sclerosis

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Findings from small randomized trial comparing nonmyeloablative HSCT with disease-modifying tx
After infections tied to unapproved stem cell treatments sent 12 people to the hospital this past year

FDA Warns Companies on Unsafe, Unapproved Stem Cell Treatments

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Patients contracting deadly infections at clinics offering the unapproved treatments
A clinical trial assessing the use of stem cells to treat heart failure patients has been paused by the U.S. National Heart

Cardiac Stem Cell Trial Halted Due to Concerns About Fake Data

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CONCERT-HF trial on hold while data and safety monitoring board conducts review
The U.S. Food and Drug Administration has launched legal action to stop two stem cell clinics from providing unapproved treatments that have caused serious

FDA Targets Clinics Offering Unapproved Stem Cell Therapies

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Clinics claim unapproved therapies can treat number of diseases and conditions, including ALS and cancer
Crowdfunding campaigns for unproven stem cell-based interventions tend to exaggerate the efficacy and underemphasize the risks

Crowdfunding Exaggerates Efficacy of Unproven Stem Cell Tx

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Crowdfunding campaigns for unproven stem cell-based interventions underemphasize risks