Tag: Stem Cells
FDA Approves Cord Blood Stem Cell Product for Blood Cancer Patients
Omisirge speeds neutrophil recovery and cuts risk of infection
Variants ID Outcomes in Adults With Leukemia in Relapse Prior to Stem Cell Transplant
Persistence of FLT3-ITD and/or NPM1 in blood associated with relapse and worse survival among acute myeloid leukemia patients
Chest CT Prior to Stem Cell Transplant Beneficial for Spotting Abnormalities
Patients with abnormal chest CT had worse overall survival, nonrelapse mortality, pulmonary-related death
Allogeneic Stem Cell Transplant Feasible for Leukemia in Elderly Patients
Overall survival 64 and 55 percent at one and two years; nonrelapse mortality 20 and 28 percent, respectively
Study Looks at Clonal Hematopoiesis in Pediatric Cancer Survivors
Clonal hematopoiesis occurs more often in pediatric cancer survivors; is associated with exposures to alkylating agents, radiation, bleomycin
ASA: Stem Cell Transplant Improves Vasculopathy in Sickle Cell Patients
No patients without evidence of vasculopathy at transplant developed stenoses or aneurysms after hematopoietic stem cell transplantation
Posoleucel Efficacious for Stem Cell Transplant Recipients
Posoleucel effective for refractory viral infections/disease, with overall response rate of 95 percent six weeks after treatment
Autologous Hematopoietic Stem Cell Transplant Slows Disability Progression in MS
Slowing of disability progression and higher likelihood of disability improvement observed compared with standard disease-modifying therapies
Bridge Therapy Between Induction, ASCT May Slow Neuroblastoma
Three-year event-free survival significantly improved for patients with end-induction stable metastatic disease receiving bridge therapy
AACR: Resistance Mechanisms to CAR-T Cell Therapy ID’d in ALL
Mechanisms of resistance detectable prior to treatment and include hypermethylation of PCR2 targets in embryonic and cancer stem cells
