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Anticholinergic medications are frequently prescribed to older adults

Burden of Anticholinergic Meds in Older Adults Must Be Considered

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Often prescribed to older adults; measures developed for quantifying anticholinergic burden
Some high-risk women who take tamoxifen to prevent breast cancer may mistake naturally occurring nausea and vomiting for side effects of the drug and stop taking it

SABCS: Tamoxifen May Be Unfairly Blamed for Side Effects

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Perceived side effects might lead some to stop taking the medication, researchers say
Glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) are associated with increased risk of gastrointestinal adverse events

GI Adverse Events Up With GLP-1 Receptor Agonists

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Risk varies based on dose, background medications, and type of GLP-1 RA
Healthy participants receiving the orally administered reversible fatty acid amide hydrolase inhibitor

Severe Neurologic Disorder With Administration of BIA 10-2474

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Phase 1 study involving healthy volunteers results in severe neurologic disorder, with one brain death
The multiple sclerosis drug alemtuzumab

Alemtuzumab May Reverse Some Disability in Newly-Diagnosed MS

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Alemtuzumab modifies disability measures favorably compared with SC IFN-β-1a
Many randomized clinical trials involving spinal manipulative therapy do not report adverse events

Many Spinal Manipulation Trials Don’t Report Adverse Events

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Significant increase in reporting of adverse events post-CONSORT statement of 2010
Statins are efficacious and safe for reducing the risk of vascular events

Review of Evidence Confirms Efficacy of Statin Therapy

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Larger absolute benefits for prolonged therapy; benefits outweigh rare cases of adverse events
Stronger warnings about the possible side effects of fluoroquinolones were issued Thursday by the U.S. Food and Drug Administration.

FDA Issues Stronger Warning on Side Effects of Fluoroquinolones

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Agency is recommending that health care providers not prescribe them for certain patients
The synthetic prostaglandin E1 analogue misoprostol has known severe side effects and should be considered in cases of postpartum hyperthermia

Misoprostol Should Be Considered in Postpartum Hyperthermia

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Report of 21-year-old with severe hyperthermia, rigors, tachycardia, transient encephalopathy
Anti-programmed cell death-1 therapy for metastatic melanoma is associated with the development of immune-related cutaneous events

Melanoma Therapy Tied to Cutaneous Adverse Events

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Anti-programmed cell death-1 therapy tied to lichenoid reactions, eczema, vitiligo