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Between 2005 and 2015

Number of Cancer Patients Using Gabapentinoids Up Since 2005

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Authors say more long-term studies of risks, efficacy of gabapentinoids needed
Patients receiving checkpoint inhibitor therapy often have acute kidney injury

Acute Kidney Injury Often Seen With Checkpoint Inhibitor Use

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8 percent of patients receiving checkpoint inhibitor therapy experienced sustained acute kidney injury
Potential anaphylactic or anaphylactoid reactions have been associated with insertion of peripherally inserted central catheters using the Sherlock tip locating system

Anaphylactic Reactions Tied to PICC Insertion With Magnetic Tip

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Anaphylactic, anaphylactoid reactions linked to PICC insertion using Sherlock tip locating system
A lawsuit over the antipsychotic drug Risperdal has led to an $8 billion punitive damages award against Johnson & Johnson and one if its subsidiaries.

$8 Billion Award Granted in Risperdal Lawsuit

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Plaintiff's attorneys say drug is linked to abnormal growth of female breast tissue in boys
Heart disease is associated with an increased risk for hospital admission for allopurinol-associated severe cutaneous adverse reactions

Heart Disease May Up Risk for Allopurinol-Linked Cutaneous AEs

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Risk for hospital admission increased for allopurinol-associated severe cutaneous adverse reactions
The risk for aortic and mitral regurgitation is increased with current and recent fluoroquinolone use

Aortic, Mitral Regurgitation Risk Up With Fluoroquinolone Use

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Risk significantly increased for current use and recent use, but not past use within 61 to 365 days
Aspirin for primary prevention of cardiovascular disease is likely to result in net benefit for some patients

Aspirin for Primary Prevention May Offer Net Benefit for Some

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Subgroups with net benefit had higher baseline CVD risk, higher levels of most established CVD risk factors
Use of the widely prescribed opioid tramadol is associated with a greater risk for developing hypoglycemia compared with almost every other opioid

Use of Pain Reliever Tramadol May Up Risk for Hypoglycemia

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Retrospective analysis of adverse events reported to FDA shows risk similar to that seen with methadone
Initiation of therapy with sodium-glucose cotransporter-2 inhibitors for type 2 diabetes mellitus is not associated with an increased risk for urinary tract infection events compared with initiation of other second-line antidiabetic medications

SGLT-2 Inhibitor Use Not Linked to Increased Risk for UTI Events

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Findings seen in propensity-matched cohorts versus receipt of DPP-4 inhibitors or GLP-1 agonists
For patients with relapsed multiple myeloma

Cardiovascular AEs Common With Carfilzomib in Multiple Myeloma

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Patients with relapsed multiple myeloma experiencing CVAEs had inferior survival