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Methotrexate Noninferior to Prednisone in Pulmonary Sarcoidosis

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Methotrexate noninferior to prednisone with regard to change from baseline to week 24 in percentage of predicted forced vital capacity

Urticaria Reported in Trial of Investigational HIV mRNA Vaccines

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7 percent of 108 healthy volunteers reported urticaria; unresolved urticaria persisted at 12 months in four participants

Exercise Helps Reduce Side Effects From Cancer Treatment

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Some benefits include mitigation of cardiac toxicity, peripheral neuropathy, cognitive impairment, and dyspnea

Many ADHD Medications Lead to Increases in Blood Pressure and Heart Rate

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Increases in hemodynamic signs seen with amphetamines, atomoxetine, lisdexamfetamine, methylphenidate, and viloxazine

MicroRNA-Based Germline Signature Predicts RT-Induced Genitourinary Toxicity in Prostate Cancer

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PROSTOX predicts late genitourinary toxicity, yielding area under the curve of 0.76

Serious Complications Seen With Acetaminophen Use in Seniors

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Risks increased for peptic ulcer bleeding, uncomplicated peptic ulcer, lower GI bleeding, heart failure, HTN, CKD

AAO: Corneal Toxicity Reported With Mirvetuximab Soravtansine

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Corneal toxicity not uncommon with MIRV treatment for primary gynecologic malignancies, usually resolves

Systemic Side Effects of COVID-19 Vaccine Tied to Greater nAB Response

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Each 1-degree Celsius increase in skin temperature after dose 2 linked to 1.8-, 3.1-fold higher nAB one and six months later

Study Identifies Factors Associated With Hydroxychloroquine Retinopathy

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Increased risk seen in association with female sex, older age, CKD stage 3 or greater, tamoxifen use

Seven Percent of Outpatients Experience One or More Adverse Event

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Overall, 23.2 percent of adverse events are preventable; 17.2 percent are serious