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Seizure Frequency Improves Over Time in Treatment-Resistant Epilepsy

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Two-thirds of patients had reduction in seizure frequency with addition of antiseizure medication

Seizure Risk Up for Seniors in Nursing Homes Prescribed Tramadol and Antidepressants

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Risk for seizures increased with concomitant use of tramadol with CYP2D6-inhibiting versus neutral antidepressants

Rate of Gabapentin Prescribing Increasing Since 2010

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Rate of dispensing almost doubled for both number of prescriptions and people from 2010 to 2016, followed by slower increase

Treatment Response to Antiseizure Medications Can Take More Than One Year

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Most participants with newly diagnosed focal episodes achieve seizure freedom; 27 percent become seizure-free with first ASM

Subcutaneous EEG System Feasible, Acceptable for Monitoring Seizures

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52 percent of the 754 seizures recorded on the subcutaneous system were not reported in patient diaries

Antiseizure Meds With Known or Uncertain Risks Continue to Be Prescribed in Pregnancy

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However, safer antiseizure medications are gaining favor

Newer Antiseizure Medications Less Likely to Be Associated With Major Malformations in Infants

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Maternal use of valproate, phenobarbital, and topiramate early in pregnancy linked to increased risk versus lamotrigine use

Socioeconomic Disparities Contribute to Frequent ED Visits for Seizure

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Increased odds of high ED visits seen for those with Medicare, Medicaid, no insurance versus private insurance

Epilepsy More Common With Frontotemporal Dementia

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Findings compared to people with Alzheimer disease and healthy controls

New Definition of Epilepsy Improves Diagnosis, Treatment

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Most newly diagnosed patients were seizure-free at 12 months of follow-up