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Ixekizumab (Taltz) appears beneficial in reducing the pain and disability of psoriatic arthritis

Ixekizumab Improves Symptoms in Patients With Psoriatic Arthritis

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Two-week and four-week ixekizumab dosing regimens improved signs and symptoms
Patients with severe psoriasis and those with mild psoriasis and concomitant psoriatic arthritis have an increased risk of uveitis

Uveitis Risk Higher Among Individuals With Psoriasis

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Increased risk with severe psoriasis, mild psoriasis with psoriatic arthritis
The presence of psoriatic arthritis

Specific Factors Influence First-Line Biologic Rx for Psoriasis

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Presence of psoriatic arthritis, weight, employment status, baseline disease severity all affect selection
Women have lower median Psoriasis Area and Severity Index scores than men

Lower Psoriasis Area, Severity Scores for Women Versus Men

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No differences in medication use before enrollment could explain these gender differences
Patients with psoriasis may have a higher risk of melanoma and hematologic cancers than the general population

Psoriasis May Up Risk of Melanoma, Hematologic Cancer

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No differences in risk observed for type of psoriasis therapy, including systemic or biologic medications
For patients with psoriasis

Musculoskeletal Symptoms Predict Psoriatic Arthritis

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Joint pain, fatigue, stiffness, worsening of physical function all predict PsA in patients with psoriasis
Patients with psoriasis who also have depression may face a much higher risk for psoriatic arthritis

Depressed Psoriasis Patients at Higher Risk of Psoriatic Arthritis

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Risk of psoriatic arthritis up 37 percent for psoriasis patients with depression
The injected drug Siliq (brodalumab) has been approved by the U.S. Food and Drug Administration to treat moderate-to-severe plaque psoriasis in adults.

FDA Approves Siliq for Plaque Psoriasis

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Injected medication approved for use by patients who've failed other treatments
About half of patients with chronic plaque psoriasis have fatigue

Fatigue Occurs in ~50 Percent With Chronic Plaque Psoriasis

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Objective measures of psoriasis disease activity are not associated with fatigue severity
Childhood psoriasis impacts parents' quality of life in multiple domains

Psoriasis Impacts QoL for Parents of Affected Children

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Negative impact on quality of life in multiple domains, especially emotional well-being