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Dapagliflozin Reduces Hospitalizations Among Patients With CKD

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Reduction seen in rate of admissions due to cardiac disorders, renal and urinary disorders, metabolism and nutrition disorders, neoplasms

FDA: No Useful Monoclonal Antibody Treatments Left Against New COVID-19 Variants

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Immunocompromised patients can still receive convalescent plasma

Bevacizumab, Aflibercept Compared for Neovascular AMD

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At the end of one year, likelihood of being weaned off treatment was higher for eyes treated with aflibercept versus bevacizumab

More Biosimilars Marketed in Germany, Switzerland Than U.S.

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Monthly treatment costs of biosimilars were higher in the United States than corresponding costs in Germany, Switzerland

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No Significant Association Found for ADHD Meds, CVD Risk

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Meta-analysis shows no significant associations for children, adolescents, or adults, for female patients, or for those with preexisting CVD

Deferiprone Not Beneficial for Newly Diagnosed Parkinson Disease

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Greater decrease seen in nigrostriatal iron content with deferiprone, but more patients have symptom progression leading to initiation of dopaminergic therapy

Buprenorphine Use in Pregnancy May Reduce Risk for Adverse Neonatal Outcomes

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Risk for preterm birth, small size for gestational age, low birth weight lower for those receiving buprenorphine versus methadone

Lecanemab Reduced Markers of Amyloid in Early Alzheimer Disease

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Moderately less decline seen in cognition and function at 18 months with lecanemab versus placebo

Use of New-to-Market Neurologic Medications Reported to Be Low

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Use of most new-to-market meds was <20 percent; costs for these medications were substantially larger

Convection-Enhanced Delivery of Topotecan Active in Glioblastoma

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Catheter pump system capable of CED of topotecan well tolerated and active in recurrent glioblastoma