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Biomarkers Elevated in Patients With Immune Checkpoint Inhibitor-Induced Myocarditis

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Elevations in creatine phosphokinase had sensitivity and specificity of 99 and 23 percent, respectively, for identifying myocarditis

DAAs Less Likely for Hep C Patients With Alcohol Use Disorder

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Those with current alcohol use disorder or abstinent with alcohol use disorder history had lower likelihood of receiving direct-acting antivirals

Drug Approved to Help Young Patients Battle a Rare Cancer

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Trial funded by the NCI has prompted the FDA to approve Tecentriq for children and adults with alveolar soft part sarcoma

Adverse Events Increased for Induced Abortion With Mifepristone-Misoprostol

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Serious adverse events are rare, occur more often with mifepristone-misoprostol versus procedural induced abortion in first trimester

ACP Updates Living Guideline on Pharmacologic Treatment of Osteoporosis

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Bisphosphonates strongly recommended for initial treatment of primary osteoporosis for postmenopausal women

Occurrence of Cardiovascular Events, Death Compared Between Thiazides

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Occurrence of major cardiovascular events, non-cancer-related deaths no lower with chlorthalidone versus hydrochlorothiazide

Progression-Free Survival Increased With Zanubrutinib in Leukemia

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Longer progression-free survival seen with zanubrutinib versus ibrutinib for patients with relapsed or refractory chronic or small lymphocytic leukemia

Congressional Report Slams FDA, Drugmaker Over Approval of Alzheimer Drug Aduhelm

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Controversy over Aduhelm stretches back to its June 2021 approval by the U.S. Food and Drug Administration

Molnupiravir Does Not Reduce COVID-19-Related Hospitalization, Death

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No reduction in COVID-19-associated hospitalizations or deaths seen among high-risk, vaccinated adults

5α-Reductase Inhibitors Linked to Depression, but Not Dementia

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Magnitude of association for finasteride and dutasteride with dementia decreased over time and became nonsignificant