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Comparative Effectiveness of Meds for Acute Low Back Pain Unclear

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Low or very low confidence in evidence for reduced pain intensity after treatment with various meds, med combos

Drug Shortages Rose by 30 Percent in 2022, U.S. Senate Report Shows

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Though 295 drugs were in shortage last year, the latest number is 130; about 15 critical drug products have been scarce for a decade

Prenatal Exposure to Phentermine-Topiramate Lower Under Safety Program

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Prevalence of pregnancy and incidence of conception were lower for phentermine-topiramate versus topiramate and other antiobesity meds

Empagliflozin Improves HbA1c in Young People With T2DM

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Significant reduction seen in HbA1c with empagliflozin, but not linagliptin, versus placebo

Weight Gain, Raised BP Risk Seen for HIV Patients Switching to Dolutegravir

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Patients switching from efavirenz to dolutegravir gain more weight at 12 months and have increased risk for hypertension

One-Quarter of Older Advanced Cancer Patients Taking Eight or More Drugs

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Polypharmacy tied to increased risk for adverse treatment outcomes, such as toxicity and early treatment discontinuation

U.S. Travelers Warned About Counterfeit Pills Containing Fentanyl in Mexico Pharmacies

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Among the towns where this may be happening are beach resort locations, such as Playa del Carmen and Tulum

FDA Advisers Back Full Approval of Paxlovid

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Panel of FDA advisers says the medication remains safe and effective for high-risk patients

Clozapine, ECT, Lithium May Prevent Suicide in Male Teens With Severe Mental Illness

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Regional clozapine, ECT, and lithium treatment frequency related to lower adolescent excess suicide mortality for 15- to 19-year-olds

Lebrikizumab Effective for Adults, Teens With Atopic Dermatitis

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In two phase 3 trials, lebrikizumab effective for primary outcome of IGA score of 0 or 1 and for achieving EASI-75