Tag: Prescription Drugs
Ubrogepant Beneficial for Treating Migraine During the Prodrome
Absence of moderate or severe headache reported in 46 and 29 percent of prodrome events that had been treated with ubrogepant, placebo
Publication Bias Inflates Apparent Efficacy of Alprazolam XR
One of five trials in the FDA review was positive; all three trials in the published literature were positive
Recommendations Developed for Atopic Dermatitis Therapies
Guidelines include strong recommendations for monoclonal antibodies and JAK inhibitors
Gantenerumab Does Not Slow Clinical Decline in Early Alzheimer Disease
Two trials show lower amyloid plaque burden with gantenerumab versus placebo at 116 weeks
Obinutuzumab Preserves Kidney Function in Lupus Nephritis
Reduction seen in risk for developing composite kidney outcome
Overall Survival Benefit Up for Pyrotinib + Capecitabine in HER2-Positive Breast Cancer
Overall survival benefit demonstrated among patients with metastatic breast cancer who had received trastuzumab and taxanes
Osimertinib + Chemo Improves Progression-Free Survival in Advanced NSCLC
Greater incidence of grade 3 or higher adverse events from any cause seen in combination group versus monotherapy
Pembrolizumab + Standard Chemotherapy Beneficial in Mesothelioma
Improvement in overall survival seen for patients receiving cisplatin or carboplatin with pemetrexed
Higher Visceral Adipose Tissue May Need Higher Infliximab Levels for IBD Remission
Both visceral adipose percentage and infliximab levels independently tied to steroid-free deep remission
Estrogen-Linked Thrombotic Biomarkers Drop After Cessation of Combo Pill
Decreases seen at week 12, with most of the decrease achieved at two and four weeks after cessation of combined hormonal contraceptives