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P2Y12 Inhibitor Monotherapy Beneficial for Patients Who Undergo PCI

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Risk for major adverse cardiac and cerebrovascular events lower compared with aspirin monotherapy for patients who undergo PCI and discontinue DAPT

ASCO: Durvalumab Plus FLOT Beneficial for Resectable Gastric, GE Junction Cancer

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Better event-free survival outcomes seen for durvalumab plus FLOT versus FLOT alone in phase 3 randomized trial

Initiation of HIV PrEP in Young Adults Rose in Recent Years

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PrEP dispensing and initiation have increased but PrEP persistence has decreased

ASCO: Elinzanetant Cuts Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy

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Findings seen in women with moderate-to-severe vasomotor symptoms associated with endocrine therapy for HR-positive breast cancer

Lamivudine Improves Visual Acuity in Center-Involved Diabetic Macular Edema

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Best corrected visual acuity improved 9.8 letters with lamivudine after four weeks, decreased 1.8 letters with placebo

ASCO: Vepdegestrant Ups Survival in ER+, HER2− Advanced Breast Cancer With ESR1 Mutations

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Progression-free survival longer with vepdegestrant than fulvestrant in subgroup with ESR1 mutations, but not in the overall population

ASCO: Encorafenib + Cetuximab + Chemo Lengthens Survival in Metastatic CRC

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Significantly longer progression-free and overall survival seen in patients with BRAF V600E mutations

ASCO: Maintenance Lurbinectedin + Atezolizumab Enhances Survival in Lung Cancer

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Findings seen for patients with extensive-stage small cell lung cancer, following standard induction therapy

Severe Exacerbations Down With As-Needed Albuterol-Budesonide for Mild Asthma

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Severe exacerbation occurred in fewer patients receiving albuterol-budesonide versus those receiving albuterol only

Intravenous Tenecteplase Beneficial Before Endovascular Thrombectomy

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Higher functional independence seen at 90 days for patients with acute ischemic stroke due to large vessel occlusion who present within 4.5 hours