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ViPOR Results in Durable Remission in Specific Subtypes of Lymphoma

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Complete responses seen in 38 percent of patients, all with non-GCB DLBCL, high-grade B-cell lymphoma with rearrangements of MYC and BCL2 or BCL6

Reteplase Superior to Alteplase Within 4.5 Hours of Ischemic Stroke

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Reteplase more likely to result in excellent functional outcome than alteplase for ischemic stroke within 4.5 hours of symptom onset

FDA Approves Augtyro for NTRK-Positive Advanced Solid Tumors

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Approval is for both TKI-naive and TKI-pretreated patients across solid tumor types

Dementia With Lewy Bodies Risk Down With α-1 Adrenergic Receptor Antagonists

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Risk for developing DLB was lower for men newly started on Tz/Dz/Az compared with those taking tamsulosin or 5ARI

Trametinib Safe, Effective for Juvenile Myelomonocytic Leukemia

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Seven of 10 children with relapsed or refractory JMML completed all 12 cycles of therapy or used trametinib as bridge to HSCT

Lebrikizumab Tied to Sustained Atopic Dermatitis Treatment Effect

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Findings seen despite negligible remaining lebrikizumab serum concentrations following treatment withdrawal

Continuing Metformin in Pregnancy Has Little Effect on Nonlive Birth

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Little to no increased risk for nonlive birth seen among women continuing metformin and adding insulin versus switching to insulin monotherapy

Paternal Metformin Use Not Linked to Major Congenital Malformations

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No significant association seen for increased risk for MCMs with metformin in monotherapy, but association suggested for metformin in polytherapy

2008 to 2021 Saw Increase in Prevalence of Chronic HTN in Pregnancy

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During study period, use of antihypertensive medications was relatively stable for those with chronic hypertension

Few Receive Meds for Opioid Use Disorder After Nonfatal Overdose

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Lower odds of fatal OD seen with filling naloxone prescription, receiving methadone or buprenorphine, receiving behavioral health assessment or crisis services