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Tenecteplase Is Reasonable Alternative to Alteplase for Ischemic Stroke

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No significant difference seen in terms of effectiveness or safety outcomes, including functional independence at discharge

FDA Approves Tremfya for Active Crohn Disease in Adults

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Tremfya is the first and only interleukin-23 inhibitor offering both subcutaneous and intravenous induction options for Crohn disease

ACP Issues Clinical Guideline for Pharmacologic Treatment of Acute Episodic Migraine

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ACP recommends adding triptan to NSAID or acetaminophen to treat moderate-to-severe acute episodic migraine

Few Nonsurgical Treatments Show Effectiveness for Low Back Pain

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Review reveals nonsteroidal anti-inflammatory drugs are effective for acute pain and five treatments are effective for chronic pain

AAD: Baricitinib Efficacious for Hair Regrowth in Teens With Severe Alopecia Areata

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Significantly more patients receiving baricitinib 2 mg, 4 mg had SALT score ≤20, ≤10 versus placebo at week 36

Roflumilast Cream 0.05 Percent Safe, Effective in Young Children With Eczema

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Significant improvement in pruritus seen within 24 hours of first application

AAD: Maintenance of Low Eczema Activity Seen After About 80 Days Off Tapinarof

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Many patients who achieved clear skin with tapinarof treatment maintained low disease activity after treatment-free interval

AAD: Ivarmacitinib 4 mg, 8 mg Efficacious for Adults With Severe Alopecia Areata

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No new safety signals or reports of deaths, thromboembolic events, or major cardiovascular events reported

Bronchodilator Responsiveness Positivity More Likely in Morning

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Significant association seen for patients referred for asthma/query asthma, but not those referred for other reasons

Remibrutinib Beneficial for Urticaria After H1-Antihistamine Treatment

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Remibrutinib results in significant improvement in composite measure of itching and hives at week 12 after second-generation H1-antihistamine treatment