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Despite evidence that has suggested metformin might have potential in cancer

AACR: Metformin Benefit Lacking in Pancreatic Ductal CA

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Survival not significantly different for pancreatic ductal adenocarcinoma patients
Opioids that have features that make them hard to abuse may be linked to a drop in both the number of prescriptions and overdoses of these drugs

Changing Opioid Rx Formulations May Help Curb Abuse

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As opioid market changed, number of prescriptions, overdoses dropped, but heroin overdoses went up
At least five different strategies may help children swallow pills and capsules more easily

Strategies Successful for Helping Children Swallow Meds

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Five strategies identified that help get the medicine down
Both residents and attending physicians are only partly compliant with national opioid prescribing and monitoring guidelines

Attending Physicians, Residents Similar in Opioid Rx Monitoring

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Residents provide more early refills; also see more patients at higher misuse risk
Immune checkpoint inhibitors show promise in treating advanced melanoma

AACR: Immune Checkpoint Inhibitors Promising in Melanoma

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Pembrolizumab, ipilimumab, and other medications harness immune cells to target cancers
Hydroxychloroquine appears to be associated with lower risk of hyperlipidemia in patients with early rheumatoid arthritis

Hydroxychloroquine May Reduce Hyperlipidemia Risk in Early RA

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Reduced risk of hyperlipidemia with hydroxychloroquine versus other DMARDs
For patients with Behçet's syndrome

Apremilast Effective for Oral Ulcers in Behçet’s Syndrome

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Reduction in number of oral ulcers per patient; greater decline in pain from ulcers with apremilast
Phenytoin appears to be neuroprotective in acute optic neuritis

AAN: Phenytoin Neuroprotective in Optic Neuritis

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Adjusted eye retinal nerve fiber layer thickness higher for those receiving phenytoin versus placebo
Medical students in personal distress may be more likely to have suboptimal attitudes about self-prescribing and personal responsibility for reporting impaired colleagues

Suboptimal Prescribing Attitudes Could Signal Personal Distress

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Med students experiencing depression, alcohol abuse less likely to report impaired colleagues
Delivery of antioxidants to the eye may be a therapeutic option for cataracts

Review Explores Challenges of Ocular Antioxidants for Cataracts

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Prospects for future research include the use of nanotechnology to deliver antioxidants