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For patients with primary hyperparathyroidism

Surgery Cuts Fracture Risk in Primary Hyperparathyroidism

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Reduced fracture risk for surgery; bisphosphonate treatment no better than observation
Expert consensus guidance has been issued regarding the use of non-statin therapies to lower cholesterol in high-risk patients. The consensus document was published online April 1 in the Journal of the American College of Cardiology to coincide with presentation at the annual meeting of the American College of Cardiology

ACC: Expert Guidance Issued for Use of Non-Statin Therapies

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Authors recommend addition of ezetimibe at 10 mg/day for higher-risk patients
Diabetes medications containing saxagliptin and alogliptin may raise the risk of heart failure

FDA Issues New Warning for Two Diabetes Medications

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Drugs containing saxagliptin or alogliptin may be linked to heart failure risk
Hydromorphone may be another treatment option for heroin addiction

Hydromorphone May Be New Treatment for Heroin Addiction

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Researchers find hydromorphone an effective, widely available, licensed choice
Early intravenous metoprolol before primary percutaneous coronary intervention does not reduce infarct size in a population with ST-segment elevation myocardial infarction

ACC: Pre-pPCI Metoprolol Doesn’t Reduce Infarct Size in STEMI

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Metoprolol cut incidence of malignant arrhythmias; was not linked to increase in adverse events
For patients with acute myocardial infarction

ACC: Losmapimod Doesn’t Cut Cardio Events After Acute MI

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In part A of trial, no reduction in risk of composite of cardiovascular death, MI, severe recurrent ischemia
For children aged 4 to 18 years

Child Mental Health Care Varies Widely in Primary Care Settings

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Prevalence of mental health diagnosis, psychotropic medication prescribing vary across U.S. practices
For patients with Parkinson's disease admitted to the hospital

Under-Dosing Worsens Prognosis for PD Patients With Infection

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Findings among patients with Parkinson's disease admitted to the hospital with pneumonia, UTI
On-demand

Continuous-Flow Production of Pharmaceuticals Feasible

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Continuous-flow synthesis of active drugs demonstrated in compact reconfigurable platform
Omalizumab is effective in patients with moderate-to-severe chronic spontaneous urticaria symptoms and angioedema unresponsive to high doses of antihistamine treatment

Omalizumab Effective for Chronic Spontaneous Urticaria

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Treatment improves quality of life, cuts angioedema recurrence