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FDA Approves Cabozantinib for Previously Treated Advanced Neuroendocrine Tumors

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Patients treated with cabozantinib survived significantly longer with no worsening of their disease compared with patients who received placebo

Pelabresib Plus Ruxolitinib Improves Underlying Myelofibrosis

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In a recent study, significantly more patients receiving the combination therapy met primary end point of reduction in spleen volume of ≥35 percent from baseline

Heart Failure Patients With Ejection Fraction Improvement Rarely Withdrawn From Meds

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Withdrawing renin-angiotensin inhibitors/angiotensin receptor-neprilysin inhibitors and mineralocorticoid receptor antagonists tied to higher one-year mortality, morbidity

Molecular Residual Disease Analysis May Predict Disease Recurrence After Lung Cancer Resection

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Molecular residual disease precedes DFS events in patients receiving osimertinib, placebo; most events occur after osimertinib discontinuation or completion

Long-Term Gantenerumab May Slow Decline in Dominantly Inherited Alzheimer Disease

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Hazard ratio for clinical decline in Clinical Dementia Rating-Sum of Boxes was 0.53 for those treated with gantenerumab the longest

FDA Approves Blujepa for Uncomplicated Urinary Tract Infections

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Medication approved for uUTIs in women and pediatric patients aged 12 years and older

Tenecteplase Is Reasonable Alternative to Alteplase for Ischemic Stroke

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No significant difference seen in terms of effectiveness or safety outcomes, including functional independence at discharge

FDA Approves Tremfya for Active Crohn Disease in Adults

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Tremfya is the first and only interleukin-23 inhibitor offering both subcutaneous and intravenous induction options for Crohn disease

ACP Issues Clinical Guideline for Pharmacologic Treatment of Acute Episodic Migraine

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ACP recommends adding triptan to NSAID or acetaminophen to treat moderate-to-severe acute episodic migraine

Few Nonsurgical Treatments Show Effectiveness for Low Back Pain

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Review reveals nonsteroidal anti-inflammatory drugs are effective for acute pain and five treatments are effective for chronic pain