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A novel antibody that targets claudin 18.2 is helping some patients with advanced gastric cancer live longer

ASCO: IMAB362 Can Lengthen Lives of Gastric Cancer Patients

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Patients with advanced disease lived longer when they received this targeted treatment
For postmenopausal women with breast cancer

ASCO: Extension of Aromatase Inhibitor Tx Benefits Breast CA

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Extension of aromatase inhibitor treatment to 10 years linked to higher rates of disease-free survival
Antacids that contain aspirin may cause stomach or intestinal bleeding in rare cases

Serious Bleeding Risks Linked to OTC Antacids Containing Aspirin

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Alka Seltzer, Bromo Seltzer among over-the-counter products vulnerable patients should avoid, FDA says
For older adults with knee osteoarthritis

Spironolactone No Benefit for Knee OA in Older Adults

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No improvements seen in symptoms, physical function, or health-related quality of life
About 18 percent of patients undergoing percutaneous coronary intervention have a contraindication to commonly used antiplatelet medications

Contraindication to Antiplatelet Rx for ~18 Percent With PCI

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Six percent of these patients receive antiplatelets; no increased mortality with contraindicated med use
Too few patients are being prescribed any of the three available medications used to treat opioid use disorder in the 30 days after hospital discharge

Meds to Treat Opioid Addiction Significantly Underused

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In 2013, just 17 percent were given medications like naltrexone after hospital discharge
A significant number of patients continue to take prescription opioids many months after joint replacement surgery

Many Still on Opioids Six Months After Total Joint Arthroplasty

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Study findings highlight growing epidemic
Diagnosis and management of heparin-induced thrombocytopenia are discussed in a review published in the May 31 issue of the Journal of the American College of Cardiology.

Vigilance Urged for Heparin-Induced Thrombocytopenia

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Heparin should be terminated on suspicion of HIT; alternative anticoagulants recommended
For patients receiving anti-epidermal growth factor receptor treatment

Prophylactic Antibiotics Cut Risk of Anti-EGFR Skin Rash

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Systematic review shows reduction in risk of developing a skin rash with prophylactic antibiotics
A decision tool (dual antiplatelet therapy [DAPT] score) improves risk prediction for continued DAPT beyond assessment of myocardial infarction history

DAPT Score Improves Risk Prediction of Continued DAPT

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Score improves prediction of benefit and harm for continued DAPT therapy beyond MI history alone