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The dipeptidyl peptidase-4 inhibitors vildagliptin and sitagliptin have similar effects on incretin hormone secretion

Vildagliptin, Sitagliptin Have Similar Effects on Incretin

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Inter-individual variability seen in L-cell feedback induced by DPP-4 inhibitors
For patients with fibromyalgia

IV Lidocaine Has No Meaningful Impact in Fibromyalgia

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No clinical manifestations for combination of lidocaine for four weeks with amitriptyline
Physicians who receive even one free meal

One Free Meal From Industry Ups Brand-Name Rx Among Doctors

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Study sheds light on a popular marketing tactic that may raise drug costs for seniors
For chemotherapy-naive men with metastatic castration-resistant prostate cancer

Tasquinimod Improves Radiographic PFS in mCRPC

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Does not improve overall survival in metastatic castration-resistant prostate cancer
Use of tenofovir disoproxil fumarate during pregnancy can reduce the rate of mother-to-child transmission of hepatitis B virus

Tenofovir Disoproxil Fumarate Can Cut HBV Transmission

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Use of TDF in pregnancy is associated with a reduced rate of mother-to-child transmission
Patients with poorly controlled cardiovascular disease risk factors could improve their prognosis by having pharmacists help manage their care

Pharmacist Involvement Can Improve Cardiovascular Care

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Patients receiving pharmacists' care lowered their estimated future risk of cardiovascular disease
There is a need for development of new anti-herpetic compounds with different mechanisms of action for herpes simplex viral keratitis

Treatment Options Reviewed for Herpes Simplex Viral Keratitis

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Options include acyclovir, valacyclovir, topical ganciclovir; need for development of new compounds
Opioid use may significantly increase mortality risk

Long-Acting Opioids May Increase Risk of All-Cause Mortality

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Much of the risk related to cardiovascular complications, not overdoses
Sales of the migraine treatment skin patch Zecuity (sumatriptan iontophoretic transdermal system) have been halted after patients reported suffering burns and scars where the patches were applied

Sales of Zecuity Migraine Skin Patches Halted

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Some users have developed skin discoloration, cracked skin, and pain where patches were applied
More than half of patients prescribed opioids receive more than they need

Many Patients Prescribed Opioids Sharing Leftover Pills

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Two new U.S. studies shed additional light on opioid epidemic