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Early initiation of antiretroviral therapy is associated with a sustained reduction in genetically-linked HIV-1 infections among sexual partners

Early Initiation of ART Cuts HIV-1 Infection in Partners

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Risk of genetically-linked partner infection 93 percent lower with early antiretroviral therapy
Metamizole seems to be safer than other nonsteroidal anti-inflammatory drugs and causes fewer gastric and duodenal ulcers in postoperative pain management

Metamizole Could Be Alternative to Classical NSAIDs

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Fewer gastric, duodenal ulcers with metamizole; limited risk of bleeding in post-op pain management
HIV transmission is highly unlikely among heterosexual couples who have sex without condoms when one partner carries the virus but takes antiretroviral therapy

Small HIV Infection Risk in Condomless Sex With Use of ART

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Study suggests transmission risk is low if infected person adheres to antiretroviral treatment
A drug used to treat leukemia

Nilotinib Shows Early Promise for Parkinson’s Disease

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Medication generally found safe, and study findings hint at a benefit
Recommendations for the use of antiretroviral therapy in HIV infection have been updated for adults

Recommendations Updated for Use of Antiretroviral Tx in HIV

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Preexposure prophylaxis for at-risk individuals; postexposure prophylaxis for after exposure
Emetine may represent a therapeutic option for human cytomegalovirus infection

Emetine Shows Promise for Human Cytomegalovirus Infection

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Inhibition with emetine occurs after virus entry but before DNA replication
Patients with rheumatoid arthritis rarely use triple therapy (methotrexate

Triple Therapy Rarely Used for Rheumatoid Arthritis Patients

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Factors tied to intensification to triple tx include age, region, outpatient visits, glucocorticoid use
Medication organization devices may cause medication-related adverse events in unintentionally nonadherent older people

Medication Organization Devices Tied to Adverse Effects

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Study identifies design elements for future trials to evaluate device effectiveness in elderly
For adults with diabetic gastroparesis

Relamorelin Beneficial in Adults With Diabetic Gastroparesis

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Drug is linked to significantly accelerated gastric emptying, reduced vomiting frequency
Neratinib and veliparib-carboplatin appear to be effective in women with specific subtypes of breast cancer

Neratinib Active in HER2-Positive, HR-Negative Breast Cancer

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And higher pathologic complete response for veliparib-carboplatin in triple-negative breast cancer