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Patients with moderate-to-severe Crohn's disease who haven't responded to other treatments may benefit from the drug ustekinumab (Stelara)

Ustekinumab Shows Promise in Crohn’s Disease

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Medication potentially helpful in those for whom other treatments haven't worked
Acid suppression therapy is associated with increased incidence of kidney stones and chronic kidney disease

ASN: Acid Suppression Therapy Linked to Kidney Stones, CKD

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Two studies show increased risk of kidney stones with PPI, H2 blocker use; CKD with PPI use
Cigarette smoking may decrease the effectiveness of medication taken during early stages of chronic kidney disease

ASN: Smoking May Negate Some Benefits of Rx Therapy in CKD

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Possibly because cigarette smoking causes oxidative stress
Metformin seems to alter gut microbiota composition

Metformin Alters Gut Microbiota Composition in Diabetes

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Higher relative abundance of A. muciniphila, SCFA-producing microbiota for metformin-treated diabetes
Palbociclib can help slow the progression of advanced breast cancer

Palbociclib Efficacious in Metastatic Breast Cancer

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Palbociclib-letrozole combination slows disease progression

American College of Rheumatology, Nov. 12-16

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The 80th Annual Meeting of the American College of Rheumatology The annual meeting of the American College of Rheumatology was held from Nov....
Medication adherence is increased with receipt of care in a patient-centered medical home

Medication Adherence Up in Patient-Centered Medical Homes

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Among matched control and medical home practices, adherence up in medical homes
For kidney transplant recipients with hepatitis C virus genotype 1 or 4 infection

Ledipasvir-Sofosbuvir Safe for Kidney Recipients With HCV

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SVR12 for all kidney transplant recipients with HCV genotype 1, 4 after 12 or 24 weeks of treatment
Cash prices of generic medicines to treat heart failure vary so widely that some patients may not be able to afford to fill all of their prescriptions

AHA: Wide Variation in Prices of Generic Heart Failure Meds

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Patients can spend from $12 to $400 a month to fill prescriptions
Bisphosphonates reduce the risk of vertebral

Findings Support Bisphosphonate Use in Men With Osteoporosis

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Reduced risk seen for vertebral and possibly nonvertebral fractures