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Treatment for subclinical hypothyroidism or hypothyroxinemia before 20 weeks of gestation is not associated with better cognitive outcomes in children

Cognitive Outcomes in Children No Better With Levothyroxine Tx

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Subclinical hypothyroidism, hypothyroxinemia tx in pregnancy not linked to improved outcomes
Antithrombotic drug use is associated with increased risk of subdural hematoma

Subdural Hematomas Rising Alongside Antithrombotic Use

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Highest odds of subdural hematoma for combined use of vitamin K antagonist and antiplatelet drug
Exposure to neuraminidase inhibitors during pregnancy is not associated with adverse neonatal outcomes or congenital malformations

Exposure to Neuraminidase Inhibitors in Utero Not Harmful

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No increased risks of adverse neonatal outcomes or congenital malformations with in utero exposure
There is doubt as to whether diazepam provides benefit in the treatment of low back pain in the emergency department environment

Diazepam Not Beneficial for Acute Low Back Pain in ER

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No better than placebo when added to naproxen, research suggests
For women with low-grade serous carcinoma of the ovary or peritoneum

Hormonal Maintenance Tx Ups PFS in Low-Grade Serous Cancer

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Significantly longer progression-free survival in low-grade serous carcinoma of the ovary or peritoneum
For older U.S. Medicare beneficiaries

DPP-4i Treatment Doesn’t Up MI, Stroke Risk in Seniors

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No increased risk for DPP-4i versus sulfonylureas, thiazolidinediones in older Medicare population
Patients transported in an ambulance specially equipped to diagnose and treat stroke on route to the hospital have a lower risk of stroke-related disability than patients who receive tissue plasminogen activator at the hospital

ASA: Pre-Hospital tPA May Reduce Stroke Disability

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Findings for patients given tPA in a mobile stroke unit
Male stroke patients are more than twice as likely as female patients to receive tissue plasminogen activator treatment within 30 minutes of hospital arrival

ASA: Male Stroke Patients Twice As Likely to Get Timely tPA

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Researchers not sure why the disparity exists
For patients with type 2 diabetes

Glucagon Receptor Antagonist Ups Blood Pressure in T2DM

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LY2409021 linked to drop in HbA1c, increases in SBP, DBP, mean arterial pressure
For patients with hereditary angioedema with C1 inhibitor deficiency

Lanadelumab Active in Angioedema With C1 Inhibitor Deficiency

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Reduced cleavage of high-molecular-weight kininogen and reduction in attacks of angioedema