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Older breast cancer survivors taking letrozole for more than the recommended five years may not live longer; however

SABCS: No Survival Benefit Seen for Letrozole Beyond Five Years

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Study found women who continued with letrozole did experience other benefits, however
For veterans with dementia

Potentially Unsafe Med Scripts Up for Dual Users With Dementia

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Rates of PUM are higher among veterans with dementia using VA-Medicare Part D system
A proposed biosimilar is comparable to trastuzumab for women with ERBB2-positive metastatic breast cancer

Biosimilar Promising for ERBB2+ Breast Cancer Treatment

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Equivalent response rate for women with ERBB2-positive metastatic breast cancer receiving taxanes
High-dose crizanlizumab treatment is associated with a significantly lower rate of sickle cell-related pain crises than placebo

ASH: Lower Rate of Sickle Cell Pain Crises With Crizanlizumab

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Lower rate of crises per year; longer median time to first, second crises with high-dose therapy
For patients with human epidermal growth factor receptor 2-overexpressing early breast cancer

Meds Don’t Cut Trastuzumab-Tied Left Ventricular Remodeling

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However, perindopril, bisoprolol do protect against declines in LVEF in HER2-positive early breast cancer
A novel selective JAK-1 inhibitor

ABT-494 Effective for Patients With Rheumatoid Arthritis

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Studies show effectiveness for those with inadequate response to MTX or at least one anti-TNF agent
A significant number of patients with HIV have strains of the virus that are resistant to both older and newer drugs

More HIV Patients Exhibiting Multidrug Resistance

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Patients resistant to older medications also have problems with newer drugs
Thirty-seven percent of premature infants receive gastroesophageal reflux medications

Preemies Often Receive Gastroesophageal Reflux Meds

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Seventy-seven percent of those on medications started after NICU discharge; prolonged use common
The experimental drug CB-839 shows promise in treating kidney cancer

Drug Shows Promise in Clear Cell, Papillary Renal Cell Cancer

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93 percent had tumor growth controlled for median of more than eight months, researchers report
Preprogrammed doses of medications that can raise the risk of falls are often set too high for older hospital patients

E-Prescribing of High-Risk Drugs May Contribute to Falls in Elderly

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Study found 41 percent of medications that can increase drowsiness were set too high for seniors