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The excessive regulatory regime at the U.S. Food and Drug Administration is an important driver of high drug prices

Excessive FDA Regulation Driving High Drug Prices

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First-in-class drugs are fast-tracked while follow-on drugs can take up to 15 years to be approved
Ivermectin has anti-inflammatory properties that could be beneficial in treatment of T-cell mediated skin inflammatory diseases

Ivermectin Has Topical Anti-Inflammatory Properties

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Topical ivermectin improves allergic skin inflammation in murine model of atopic dermatitis
Pyridoxine-doxylamine (Diclectin)

Data on Effectiveness of Morning Sickness Drug May Be Flawed

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Original unpublished 1970s study results on pyridoxine-doxylamine may be deficient, authors say
For patients with advanced unresectable hepatocellular carcinoma

Sorafenib Effect on HCC Survival Depends on Hepatitis Status

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Findings in meta-analysis of individual patient data for advanced unresectable hepatocellular carcinoma
From 2000 to 2011 there were shifts in the treatment of advanced-stage non-small-cell lung cancer

2000 to 2011 Saw Shift in Treatment for Advanced NSCLC

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Rise in use of pemetrexed, erlotinib, bevacizumab; longest treatment duration with these agents
For high-risk women

Letrozole Tops Aspirin for Halting Ovarian Hyperstimulation

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Decreases incidence of moderate and severe early-onset ovarian hyperstimulation syndrome
After metformin failure

Sequential Empagliflozin, Linagliptin Diabetes Tx Effective

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Glucose control most probably mediated by effects on alpha- and beta-cell function
Fenofibrate therapy may reduce cardiovascular disease in statin-treated patients with diabetes and dyslipidemia

Fenofibrate May Reduce CVD in Patients With DM, Dyslipidemia

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No reduction in primary outcome for 4,644 ACCORD participants followed for median of 9.7 years
For patients with chronic kidney disease

Metformin Tied to Better Clinical Outcomes in CKD, CHF, CLD

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Reduced all-cause death for chronic kidney disease, congestive heart failure, chronic liver disease
The American College of Physicians has updated recommendations on the oral pharmacologic treatment of type 2 diabetes in adults. The clinical practice guideline update was published online Jan. 3 in the Annals of Internal Medicine.

ACP Updates Recommendations for Oral Medications in T2DM

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Recs serve as update to 2012 American College of Physicians guideline