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Long-term metformin use is associated with lower serum vitamin B12 concentration

Metformin Use Linked to Less Vitamin B12 Measurement

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Metformin users are less likely to receive vitamin B12 testing after adjustment for confounding variables
For men with testicular cancer undergoing retroperitoneal lymph node dissection

ASCO: Alvimopan Helpful for Men Undergoing Testicular CA Surgery

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Reduction in mean hospital length of stay and enhanced gastrointestinal recovery with alvimopan
For individuals with dysregulated type 2 diabetes

Liraglutide May Blunt Impact of Exercise in Dysregulated T2DM

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Improvement in early diastolic myocardial tissue velocity in placebo, not liraglutide group
For patients with type 2 diabetes mellitus

Dulaglutide Linked to Higher Adherence in T2DM

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Higher adherence, lower discontinuation versus exenatide once weekly or liraglutide
The risks of adverse events are similar with short-term use of typical and atypical antipsychotic medications after cardiac surgery in seniors

Similar Adverse Event Risk for Typical, Atypical Antipsychotics

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However, greater use of brain imaging associated with atypical APMs after cardiac surgery in seniors
Lixisenatide is more effective than placebo for older patients with uncontrolled diabetes on their current medication

Lixisenatide Beneficial in Seniors With Uncontrolled Diabetes

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Improved HbA1c reduction versus placebo in older patients uncontrolled on current medications
For women with early-stage

Cholesterol Lowering Rx Cuts Recurrence in Breast Cancer

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Initiation of CLM during endocrine tx tied to improved disease-free survival, recurrence-free intervals
First-line therapy for patients with low back pain should be simple non-pharmacological remedies -- from heat wraps to physical therapy

ACP Issues Guideline for Treating Acute, Subacute, Chronic LBP

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Recommendations state opioids should be last resort for pain
For patients with rheumatoid arthritis

Short-Course Tocilizumab May Up Hep B Reactivation in RA

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Three patients with chronic HBV infection had reactivation, but they were asymptomatic
There has been a sharp rise in the number of American seniors who take three or more medications that affect their central nervous system

Use of Multiple CNS-Affecting Drugs Increasing Among Seniors

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Psychiatrist cautions doctors and patients to consider risks and benefits of each drug