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Open-label placebos are associated with a positive effect compared with no treatment in a variety of clinical conditions

Positive Clinical Effects Seen for Placebos Without Deception

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Findings based on five studies involving patients with IBS, depression, allergic rhinitis, back pain, ADHD
From 2004 to 2015 there were decreases in the prevalence of advanced disease at initiation of antiretroviral therapy in 10 high-burden countries

Prevalence of Advanced HIV at ART Initiation Decreasing

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Decreases seen in Haiti, Mozambique, Namibia, Nigeria, Swaziland, Uganda, Vietnam, Zimbabwe
There is little agreement between the American Society of Clinical Oncology Value Framework and European Society for Medical Oncology Magnitude of Clinical Benefit Scale

ASCO: Agreement Lacking With ESMO on Most Effective Drugs

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Negative correlation identified for ASCO benefit score with monthly incremental drug costs
Two new medications that target specific genetic mutations may improve survival for patients with specific types of advanced non-small-cell lung cancer

ASCO: Novel Meds Show Promise in Advanced NSCLC

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Results presented from two phase III trials
Combining low doses of several different antihypertensive medications may be better than using a standard dose of just one drug

Combo of Several Meds at Smaller Doses May Boost HTN Care

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Researchers posit smaller doses of several drugs better than standard dose of just one medication
Free meals

ASCO: Industry Perks Influence Physicians’ Choice of Cancer Rx

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Even relatively small payments appear to make a difference, researchers say
Olaparib (Lynparza) monotherapy can provide a significant benefit over standard therapy in women with human epidermal growth factor receptor type 2-negative metastatic breast cancer and a germline BRCA mutation

ASCO: Olaparib Efficacious in BRCA-Related Breast Cancer

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May offer a new treatment for women with advanced BRCA-related disease, researchers say
In men with advanced prostate cancer

ASCO: Abiraterone Extends Survival in Metastatic Prostate CA

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Side effects noted with use of abiraterone similar to those already found in patients taking the drug
The methylene tetrahydrofolate reductase (MTHFR) gene A1298C polymorphism does not appear to be related to methotrexate efficacy or toxicity in patients with rheumatoid arthritis

MTHFR A1298C Polymorphism Not Linked to MTX Outcomes in RA

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No significant link for MTHFR gene A1298C polymorphism with methotrexate efficacy, toxicity
More Americans with HIV are adhering to antiretroviral therapy regimens

Antiretroviral Regimen Adherence Up for Americans With HIV

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But too many still stop taking drugs a few years after diagnosis