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Lowering of plasma uric acid with febuxostat is associated with a modest reduction in systolic blood pressure in patients with type 1 diabetes mellitus

Plasma Uric Acid Lowering Tied to Drop in Systolic BP in T1DM

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Febuxostat has modest BP-lowering effect, with no impact on arterial stiffness, urinary nitric oxide
A growing number of U.S. emergency departments are giving patients medication through the nose instead of via injections or intravenously

ERs Administering More Medications Intranasally

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Many benefits to nasal administration, including reduction in spread of infection
Apomorphine may help patients with advanced Parkinson's disease when levodopa stops working

AAN: Apomorphine May Shorten ‘Off’ Time for Parkinson’s Patients

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Study finds apomorphine cuts the time until levodopa kicks in for those with advanced disease
For patients with type 2 diabetes who initiate metformin

Early Glycemic Control With Metformin Cuts CVD Events

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Early glycemic control and magnitude of HbA1c reduction predict cardiovascular events, death
In a case report published online April 17 in the Journal of Clinical Pharmacy and Therapeutics

Case Report Describes Adverse Reaction to Clindamycin

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Patient developed acute generalized exanthematous pustulosis after vancomycin, clindamycin use
A dosage of 1 g intravenous acetaminophen every six hours yields serum concentrations below 10 µg/mL for critically ill multiple-trauma patients

1-g IV Acetaminophen Dose May Be Insufficient in Multiple Trauma

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Administration at recommended dosage yields serum concentrations below 10 µg/mL
A quality improvement initiative that combines education

QI Intervention Aids Medication Safety for Elderly in ER

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Intervention combines education, clinical decision support, provider feedback
Use of an electronic medication administration record application can reduce the rate of medication errors in medication administration recording

Electronic Drug Administration Record App Cuts Errors

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Decline in rate of medication errors in medication administration recording post-implementation
Hoping to cut the use of antipsychotic drugs in nursing home residents

Antipsychotic Medication Use Can Be Reduced in Dementia Patients

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New method helps curb undesirable behavior by recognizing dementia patients' unmet needs
Ularitide has a favorable physiological effect in patients with acute heart failure

Favorable Physiological Effect for Ularitide in Acute Heart Failure

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Greater reductions in systolic blood pressure, levels of N-terminal pro-brain natriuretic peptide