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Histologic Response Up With Benralizumab for Eosinophilic Esophagitis

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Significantly more patients had histologic response with benralizumab than placebo, but no significant difference seen in dysphagia symptoms

Dupilumab Ups Histologic Response for Pediatric Eosinophilic Esophagitis

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Significant improvements seen in histologic, endoscopic, and transcriptomic measures in higher-exposure dupilumab regimen

PIK3CA Could Guide Use of COX-2 Inhibitors in Treatment for Colon Cancer

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Patients with stage III resected colon cancer with PIK3CA gain-of-function mutations treated with celecoxib had improved DFS, OS

Glofitamab + GemOx Superior to Rituximab + GemOx for Lymphoma

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Significant overall survival benefit seen for Glofit-GemOx at primary and follow-up analysis

Decrease in Oral Contraceptive Fills Seen After Dobbs Ruling

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Fills for emergency contraceptives increased during the first year after Dobbs in states that became the most restrictive and comparison states

Atogepant Efficacious for Patients With Chronic Migraine

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Reduction seen in monthly headache days, monthly migraine days, and acute medication use days

Abrocitinib Effective, Tolerated for Prurigo Nodularis, Chronic Pruritus

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Decrease in Peak Pruritus Numeric Rating Scale for PN, chronic pruritus of unknown origin patients

ADHD Meds May Help Control Opioid Use Disorder in Pregnancy

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Additional benefits include increased buprenorphine initiation, decreased methadone initiation, and improved buprenorphine retention

SNP rs13194504 AA Genotype Linked to Severity of Tardive Dyskinesia

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AA genotype linked to reduced severity, but not occurrence, of TD; no association seen for rs210133 with TD occurrence, severity

Nonsignificant Survival Benefit Seen for Dabrafenib, Trametinib in Melanoma

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Consistent survival benefit seen across several prespecified subgroups, including those with a BRAF V600E mutation