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For patients with super-refractory status epilepticus

Brexanolone Tolerated in Super-Refractory Status Epilepticus

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Associated with high rate of third-line agent weaning; no serious adverse events attributed to the drug
Several significant interactions can occur between cannabidiol and antiepileptic drugs

Interactions Occur With Cannabidiol, Antiepileptic Drugs

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Most observed mean level changes fall within accepted therapeutic range
For men with nonmetastatic prostate cancer who are receiving androgen deprivation therapy

Osteoporosis Meds Up BMD in Nonmetastatic Prostate Cancer

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Review shows improved bone mineral density in men receiving androgen deprivation therapy

mAb Glucagon Receptor Blocker Suitable for Further Development

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REGN1193 inhibited glucose increase stimulated by glucagon in dose-dependent manner

Ipragliflozin Beneficial in T2DM Complicated by Liver Disease

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Effect similar to pioglitazone, with reduction in body weight, abdominal fat only for ipragliflozin

Genetic Variation Impacts Pharmacokinetics of Exemestane

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Significant differences in plasma exemestane area under the curve for OATP1B1 genotype groups

In Utero Psychotropics + Opioids Up Neonatal Drug Withdrawal

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Risk of withdrawal increased two-fold with in utero exposure to two or more psychotropics plus opioids

APA: Reasons for Underuse of Buprenorphine by PCPs ID’d

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Doctors not willing to increase prescribing due to lack of belief in agonist tx, lack of time for more patients

Canagliflozin Delays Increase in Certain CV Biomarkers in T2DM

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Canagliflozin may reduce CV, heart failure risk over two years versus placebo in older patients with T2DM

ABP 501, Adalimumab Biosimilar, Safe and Effective, for Psoriasis

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Findings based on comparison over 52 weeks, including single transition