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An appointment-based model which synchronizes medication refills to improve medication adherence is associated with improvement in medication-taking behavior

Medication Adherence Up With Refill Synchronization Model

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Improvement in medication-taking behavior; cost savings over one year for HTN, DM, hyperlipidemia
β-blocker use is not associated with reduced mortality after acute myocardial infarction without heart failure or left ventricular systolic dysfunction

β-Blocker Use Not Linked to Reduced Mortality After AMI

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No significant difference in mortality for MI patients without HF, LVSD with, without β-blocker use
For patients with high-risk vascular disease

Evacetrapib Appears Futile in High-Risk Vascular Disease

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No reduction in primary end point events, including death from cardiovascular causes, MI, stroke
There is a substantial financial burden for Medicare beneficiaries with myeloma who do not receive a low-income subsidy for orally-administered anticancer therapy

High Costs for Myeloma Patients Not Getting Low-Income Subsidy

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For those aged 75 to 84 years, LIS receipt linked to increased odds of receiving immunomodulatory drugs
In a case report published online May 23 in the Annals of Internal Medicine

Severe Cutaneous Adverse Effect From Tocilizumab Described

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Diffuse, persistent, pruritic maculopapular rash developed 10 days after tocilizumab treatment
For patients with breast cancer receiving endocrine therapy

Daily Texting Effectively Monitors Rx Adherence, Side Effects

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Most patients with breast cancer taking endocrine therapy report intervention helpful in taking drugs
Suramin

Sleeping Sickness Medication May Help Lessen ASD Symptoms

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Small study produced positive results with suramin, but more research needed
Ixekizumab (Taltz) appears beneficial in reducing the pain and disability of psoriatic arthritis

Ixekizumab Improves Symptoms in Patients With Psoriatic Arthritis

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Two-week and four-week ixekizumab dosing regimens improved signs and symptoms
For patients with rheumatoid arthritis

Little Benefit for Etanercept-MTX Before Triple Therapy in RA

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First-line etanercept-methotrexate would result in 0.15 additional lifetime QALY, at cost of $77,290
Two separate research groups say they've successfully reduced cholesterol in humans by using different methods to block the angiopoietin-like 3 (ANGPTL3) gene. The findings were published online May 24 in the New England Journal of Medicine.

Targeting ANGPTL3 Can Significantly Lower Cholesterol

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Two trials show promise for non-statin approach to cardiovascular disease prevention