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States that let doctors prescribe drugs to treat chlamydia or gonorrhea in both partners when only one makes an office visit have lower rates of the sexually transmitted infections

Expedited Partner Therapy Helps Reduce STI Incidence

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Lower chlamydia, gonorrhea rates seen when one person can obtain treatment for both partners
or patients aged 6 to 11 years with cystic fibrosis homozygous for F508del-cystic fibrosis transmembrane conductance regulator

Lumacaftor, Ivacaftor Linked to Improved Lung Function in CF

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Findings in patients aged 6 to 11 years with cystic fibrosis homozygous for F508del-CFTR
A host of new medications that appear to prevent migraine headaches are in the final stages of testing and approval in the United States

Several New Medications in the Pipeline to Prevent Migraine

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New injectable drugs work by targeting calcitonin gene-related peptide
Survivors of adolescent and young adult cancer are more likely to report cost-related medication nonadherence

Young CA Survivors More Often Have Cost-Related Nonadherence

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Risk of nonadherence was lower for survivors reporting a usual source of care than those without
For patients with schizophrenia

Relapse Down With Clozapine, Injectables in Schizophrenia

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Risk of rehospitalization substantially lower with long-acting injectables versus oral equivalents
In a report published online June 5 in the Journal of Clinical Pharmacology

Researchers Target Zolmitriptan Dosing for Pediatric Migraine

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Study supports body-weight dosing of 5.0 mg and 2.5 mg for children >50 kg and <50 kg, respectively
Sodium-glucose cotransporter 2 inhibitors appear to increase the risk of diabetic ketoacidosis in patients with type 2 diabetes

SGLT2 Inhibitors Linked to Increased Risk of Ketoacidosis

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Associated with approximately twice the risk of DKA compared to DPP4 inhibitors
Lithium is linked to an increased risk of heart malformations in infants born to women taking the drug during pregnancy

Lithium’s Risk to Fetus May Be Lower Than Previously Thought

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Increased risk of cardiac defects seen, but magnitude of effect smaller than previously postulated
Open-label placebos are associated with a positive effect compared with no treatment in a variety of clinical conditions

Positive Clinical Effects Seen for Placebos Without Deception

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Findings based on five studies involving patients with IBS, depression, allergic rhinitis, back pain, ADHD
From 2004 to 2015 there were decreases in the prevalence of advanced disease at initiation of antiretroviral therapy in 10 high-burden countries

Prevalence of Advanced HIV at ART Initiation Decreasing

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Decreases seen in Haiti, Mozambique, Namibia, Nigeria, Swaziland, Uganda, Vietnam, Zimbabwe