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In Utero Psychotropics + Opioids Up Neonatal Drug Withdrawal

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Risk of withdrawal increased two-fold with in utero exposure to two or more psychotropics plus opioids

APA: Reasons for Underuse of Buprenorphine by PCPs ID’d

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Doctors not willing to increase prescribing due to lack of belief in agonist tx, lack of time for more patients

Canagliflozin Delays Increase in Certain CV Biomarkers in T2DM

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Canagliflozin may reduce CV, heart failure risk over two years versus placebo in older patients with T2DM

ABP 501, Adalimumab Biosimilar, Safe and Effective, for Psoriasis

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Findings based on comparison over 52 weeks, including single transition

Inappropriate Med Use High in Cognitively Impaired Seniors

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Prevalence of potentially inappropriate medication use higher for frail seniors with cognitive impairment

Review: Levetiracetam Best Monotherapy for Partial Seizures

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First-line tx sodium valproate tops carbamazepine, topiramate for generalized onset seizures

Are Clinicians Overprescribing Gabapentinoids for Pain?

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Non-trivial side effects, no robust evidence for off-label use of gabapentinoids for other types of pain
Isoniazid monotherapy

Meta-Analysis Compares Efficacy of Therapies for Preventing TB

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Isoniazid, rifampicin monotherapy, combination therapies can prevent active TB in latent TB infection
More interventions are needed to meet the target of hepatitis C virus elimination

More Progress Needed for Hep C Elimination in Country of Georgia

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Overall, 84.1 percent of those tested for HCV RNA after treatment had no detectable virus in their blood
For infants with gastroesophageal reflux disease

Variation in Management for Infants With GERD

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Variation in overall utilization of anti-reflux surgery, and in surgical and diagnostic approach