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Use of androgen-deprivation therapy may increase the risk of certain cardiovascular conditions in men with prostate cancer

Androgen-Deprivation Therapy May Carry Cardiovascular Risks

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Findings in men with clinically localized prostate cancer initially under active surveillance
Bivalirudin is not associated with a lower rate of the composite of any cause death

No Reduction in Composite End Point for Bivalirudin in PCI

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Patients receiving bivalirudin vs heparin saw no reduction in composite of death, MI, major bleeding
For patients with atrial fibrillation who undergo percutaneous coronary intervention

Dual Therapy Noninferior to Triple Therapy for A-Fib With PCI

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And lower risk of bleeding with dabigatran and P2Y12 inhibitor dual therapy versus triple therapy
Canakinumab at a dose of 150 mg every three months is associated with reduced rate of cardiovascular events among patients with previous myocardial infarction

Canakinumab 150 mg Tied to Reduced Rate of Cardiac Events

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150-mg dose met prespecified threshold for significance for primary and secondary end points
An immune-modulator anti-inflammatory drug

Diacerein Reduces Mean Hemoglobin A1c Levels in T2DM

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Peak of effect occurred at 24th week of treatment; attenuated toward nonsignificance at 48th week
There has been a significant decline in the risk of secondary cancers after Kaposi sarcoma in the era of highly-active antiretroviral therapy

ART Era Has Changed Secondary Cancers After Kaposi Sarcoma

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Certain cancers -- ALL and cancers of the tongue, penis -- becoming more common
At its current price

More Evidence Evolocumab Exceeds Cost-Effectiveness

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Findings for addition of evolocumab to standard tx in atherosclerotic cardiovascular disease
For patients with psoriasis receiving long-term methotrexate sodium therapy

Noninvasive Test for NASH, Fibrosis in Patients With Psoriasis

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Correlation for cumulative methotrexate dose with higher score on NASH FibroSure in women
Too many patients with migraines are prescribed opioids

Opioids Often Prescribed Unnecessarily for Migraine

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And many patients may not be getting recommended medications
The risk of acute kidney injury is not increased for new sodium-glucose cotransporter-2 inhibitor users

No Increase in Acute Kidney Injury Risk for SGLT2 Users

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Using data from two health systems, no increased risk seen in AKI, even after adjustment for covariates