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Methotrexate and azathioprine appear to be effective and safe as maintenance treatments in moderate-to-severe atopic dermatitis for up to five years

Methotrexate, Azathioprine Seem Safe Long-Term for Dermatitis

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For up to five years as maintenance treatments for moderate-to-severe atopic dermatitis
Compared to placebo

Pioglitazone Associated With Lower Blood Leptin in Diabetes

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In T2DM, leptin levels are lower with pioglitazone than placebo but not oral antidiabetic drugs
For patients undergoing catheter ablation for nonvalvular atrial fibrillation

Interruption of Apixaban Doesn’t Impact Bleeding in A-Fib

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Similarly low rate of thromboembolic events with uninterrupted, minimally interrupted apixaban
Varenicline is associated with reduced heavy drinking among men and with increased smoking abstinence

Varenicline Linked to Reduction in Heavy Drinking in Men

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Also associated with smoking abstinence in overall sample of participants
A levonorgestrel-releasing intrauterine device is effective in the majority of patients undergoing conservative treatment for low-risk endometrial cancer and complex atypical hyperplasia

Levonorgestrel IUD Feasible for Low-Risk, Early Uterine Cancer

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Majority of women responded well and returned to normal histology in six months
Once-daily capsules containing a combination of minoxidil and spironolactone appear to be safe and effective for the treatment of female pattern hair loss

Drug Combo Proves Effective for Pattern Hair Loss in Women

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Once-daily minoxidil, spironolactone combo appears safe and effective
For healthy adults and individuals with well-controlled type 2 diabetes

DPP-4 Inhibitor Has Dissociated Effects on β-Cell Function

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Single dose of sitagliptin linked to increases in standardized insulin secretion, active GIP, GLP-1
Switching dual antiplatelet therapy from aspirin plus ticagrelor or prasugrel to aspirin plus clopidogrel after acute coronary syndrome provides benefits regardless of initial platelet reactivity

Switching Dual Antiplatelet Therapy Beneficial After ACS

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Greatest benefit seen in patients with low on-treatment platelet reactivity
Among patients with acute respiratory distress syndrome

Cisatracurium Ups Some ARDS Outcomes Versus Vecuronium

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No difference in mortality or hospital days but fewer ventilator and intensive care unit days
For patients with type 2 diabetes mellitus undergoing non-cardiac surgery

Pre-Op Liraglutide Cuts Post-Op Plasma Glucose in T2DM

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Preoperative administration of liraglutide linked to lower post-op glucose, increase in pre-op nausea