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The therapeutic significance of losartan in Marfan syndrome may lie in its ability to activate protective endothelial function

Losartan May Improve Endothelial Function in Marfan Syndrome

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Therapeutic importance may be increased in endothelial nitric oxide release, not ATR1 inhibition
For patients with acute coronary syndrome

Direct Oral Anticoagulants Plus Antiplatelets Effective in ACS

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Pronounced benefit for patients with STEMI, but no significant effect for patients with NSTE-ACS
A model has been developed to predict overall survival for patients with advanced urothelial carcinoma treated with atezolizumab

Prognostic Model Developed for Immunotx of Urothelial Cancer

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Model, based on six factors, predicts overall survival for patients treated with atezolizumab
For patients with metastatic renal cell carcinoma

Atezolizumab + Bevacizumab Shows Benefit in Met Renal CA

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Progression-free survival benefit for patients with untreated metastatic renal cell carcinoma
For men with non-metastatic castration-resistant prostate cancer

Apalutamide Active in Castration-Resistant Prostate Cancer

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Apalutamide prolongs metastasis-free survival in non-metastatic castration-resistant prostate cancer
Compliance with guideline-directed medical therapy is low

Guideline-Directed Medical Tx Adherence Low Post CABG

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Compliance higher in PCI than CABG, but remains low in contemporary clinical trials
Once-daily treatment with glecaprevir-pibrentasvir appears safe and effective for the treatment of hepatitis C virus genotype 1 or 3

Glecaprevir-Pibrentasvir Effective Treatment for HCV Genotypes 1, 3

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Once-daily treatment for eight or 12 weeks yields high rates of sustained virologic response
Glucagon is being underutilized in the prehospital and outpatient setting

Glucagon Underutilized in Prehospital, Emergency Settings

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Diabetic problem often incorrectly coded by dispatch; paramedic access to give glucagon also an issue
Pharmacist feedback and education is effective at reducing prescription writing errors by junior doctors in an inpatient setting

Pharmacist Education May Cut Junior Doctor Prescription Errors

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Regular and targeted feedback by pharmacists reduces Rx errors; effect of e-learning tools unclear
For patients with intermediate risk of cardiovascular disease

ASA: Combo of BP, Cholesterol Meds Tied to Reduced Stroke Risk

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44 percent drop in stroke for those with intermediate CVD risk receiving candesartan/HCTZ, rosuvastatin