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Oral semaglutide is associated with better glycemic control than placebo among type 2 diabetes patients with insufficient glycemic control

Glycemic Control Up With Oral Semaglutide in Type 2 Diabetes

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Phase 3 studies next to assess longer-term/clinical outcomes, safety
For patients with venous thromboembolism

No Increased Risks for DOAC Use Versus Warfarin in VTE

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Direct oral anticoagulants not linked to increased risk of major bleeding, death in venous thromboembolism
Adding a sulfonylurea or metformin to insulin is associated with approximately a 1 percent reduction in hemoglobin A1c

Clinical Evidence Synopsis Published for T2DM

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Adding sulfonylurea or metformin to insulin decreases HbA1c about 1%
Internal medicine patients are frequently prescribed potentially inappropriate medications (PIMs)

Screening Tools Identify Potentially Inappropriate Meds

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However, substantial proportion of PIMS identified in internal medicine ward are not clinically relevant
Oral semaglutide is associated with better glycemic control than placebo among type 2 diabetes patients with insufficient glycemic control

Glycemic Control Up With Oral Semaglutide in Type 2 Diabetes

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Phase 3 studies next to assess longer-term/clinical outcomes, safety
High-volume continuous venovenous hemodiafiltration and resin-sorbent hemoperfusion is effective for eliminating metformin

Venovenous Hemodiafiltration Improves Metformin Toxicity

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Case report describes treatment of female patient who attempted suicide with metformin overdose
More than one-quarter of college students report believing that nonmedical use of prescription stimulants can improve academic performance

Many College Students Believe Stimulants Can Boost Grades

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More frequent use of alcohol, marijuana also tied to increased likelihood of prescription stimulant use
For patients with stage 4 or 5 chronic kidney disease and hepatitis C virus infection

High Sustained Response Rate for Glecaprevir, Pibrentasvir in HCV

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12-week therapy results in high rate of sustained virologic response for patients with CKD, hepatitis C
The Multidisciplinary Multistep Medication Review is effective for discontinuation of inappropriate medication among elderly nursing home residents without a decline in their well-being

3MR Intervention Effective for Discontinuing Inappropriate Meds

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Multidisciplinary Multistep Medication Review is effective for use in frail nursing home residents
The overall incidence of adverse effects and serious adverse effects is similar in patients with type 2 diabetes mellitus taking dapagliflozin or placebo

Rate of Adverse Effects for Dapagliflozin Similar to Placebo

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Although genital infections, renal function AEs found more frequently with dapagliflozin than placebo