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Tag: Prescription Drugs

A novel oral dosage form enables sustained release of antiretrovirals

Week’s Worth of HIV Meds in a Single-Dose Capsule Feasible

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Oral platform delivers three antiretrovirals for up to seven days after single administration
Fluorouracil application can reduce the risk of surgery for squamous cell carcinoma for one year among patients with a history of keratinocyte carcinomas

Fluorouracil Tied to Reduced Surgery for Squamous Cell CA

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Reduced risk of squamous cell carcinoma, but not basal cell carcinoma, for one year in at-risk veterans
Esketamine seems to be efficacious and safe for patients with treatment-resistant depression

Esketamine Safe, Effective for Treatment-Resistant Depression

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Change in Montgomery-Åsberg Depression Rating Scale score superior for esketamine versus placebo
Although patients with pre-existing autoimmune disease who receive checkpoint inhibitors (CPIs) are at risk for exacerbation of their disease

Immune-Related Adverse Events Up With Checkpoint Inhibitors

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Most patients with cancer, autoimmune disease have improvement in events without discontinuing therapy
For patients with chronic obstructive pulmonary disease

CVD Risk Up With β2-Agonist, Antimuscarinic Antagonist Start

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New use of long-acting β2-agonists, antimuscarinic antagonists tied to higher CVD risk in first 30 days
For patients with acute severe ulcerative colitis

Predictors of Infliximab Response in Ulcerative Colitis Identified

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Baseline Mayo Endoscopic Score, CRP/albumin ratio predict treatment response and risk for colectomy
Few modern

Few Immuno-Oncology Agents Reach ASCO Efficacy Thresholds

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Durable survival, response rates rarely recognized as significant by current oncology value frameworks
Pharmaceutical aids are not effective for increasing long-term smoking cessation

Pharmaceutical Aids Not Found to Be Helpful for Smoking Cessation

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No evidence that varenicline, bupropion, or nicotine replacement increase probability of abstinence
From 2002 to 2015 there was a substantial increase in gabapentinoid use

Increase Seen in Gabapentinoid Use From 2002 to 2015

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More than three-fold increase in percentage of adults using gabapentin and/or pregabalin
Across cancers

Out-of-Pocket Costs Correlate With Receipt of Cancer Care

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Across cancers, higher costs tied to higher rates of oral prescription abandonment, delayed initiation