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Tag: Prescription Drugs

Glucagon is being underutilized in the prehospital and outpatient setting

Glucagon Underutilized in Prehospital, Emergency Settings

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Diabetic problem often incorrectly coded by dispatch; paramedic access to give glucagon also an issue
Pharmacist feedback and education is effective at reducing prescription writing errors by junior doctors in an inpatient setting

Pharmacist Education May Cut Junior Doctor Prescription Errors

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Regular and targeted feedback by pharmacists reduces Rx errors; effect of e-learning tools unclear
For patients with intermediate risk of cardiovascular disease

ASA: Combo of BP, Cholesterol Meds Tied to Reduced Stroke Risk

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44 percent drop in stroke for those with intermediate CVD risk receiving candesartan/HCTZ, rosuvastatin
For patients with dementia with Lewy bodies

Adjunct Zonisamide Beneficial in Dementia With Lewy Bodies

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Zonisamide as an adjunct to levodopa improves parkinsonism without worsening cognitive function
Prior authorization requirements are greater for proprotein convertase subtilisin/kexin type 9 inhibitors than for other cardiometabolic drugs

Greater Prior Authorization Requirements Seen for PCSK9i Rx

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PA requirements are more extensive for PCSK9is than for other cardiometabolic drugs
Doxylamine-pyridoxine may be beneficial for nausea and vomiting symptoms in early pregnancy

Value of Doxylamine-Pyridoxine Questioned in Early Pregnancy

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Greater improvement in symptom scores versus placebo, but clinical relevance unclear
A case of remission of psoriasis after treatment of chronic hepatitis C virus has been described in a research letter published online Jan. 16 in the Annals of Internal Medicine.

Psoriasis Remission Described After Hepatitis C Virus Treatment

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Case report: After initiation of ledipasvir-sofosbuvir, HCV RNA decreased, and skin lesions improved
Patients with desmoplastic melanoma have a high level of objective tumor response to treatment with antibodies to block programmed cell death 1 (PD-1) or PD-1 ligand

High Response of Desmoplastic Melanomas to PD-1 Blockade

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Higher percentage of PD-L1-positive cells in the tumor parenchyma of desmoplastic melanomas
Rituximab has better efficacy and lower discontinuation rates than other disease-modifying treatment choices for newly diagnosed relapsing-remitting multiple sclerosis

Rituximab Tops Other Disease-Modifying Tx Options in MS

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Better efficacy, lower discontinuation rate in newly diagnosed relapsing-remitting multiple sclerosis
The use of idalopirdine does not improve cognition versus placebo over 24 weeks of treatment for patients with mild-to-moderate Alzheimer's disease

Idalopirdine May Not Improve Cognition in Mild Alzheimer’s

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Findings from three randomized trials show no improvement in cognition vs. placebo over 24 weeks