Tag: Prescription Drugs
Adipocytes Metabolize, Inactivate Daunorubicin
Adipocytes metabolize daunorubicin to daunorubicinol, reducing its anti-leukemia effect
Lymphoma Risk Up With Thiopurine, Anti-TNF Tx in IBD
Risk higher for those exposed to combination therapy versus thiopurine or anti-TNF monotherapy
Sodium Oxybate Promising for Parkinson’s, Daytime Sleepiness
Improvements in subjective sleep quality, objectively measured slow-wave sleep duration
Sertraline Treatment No Benefit for Depressive Symptoms in CKD
No improvement for patients with MDD and chronic kidney disease without dialysis dependence
Warfarin Use Linked to Reduced Incidence of Cancer
Reduced incidence rate ratio in all cancer sites and in prevalent cancer sites among adults aged >50
ASN: PPIs Associated With Increased Risk of Kidney Disease
Risk for both chronic kidney disease, end-stage renal disease higher with proton pump inhibitor use
ASN: Tolvaptan Slows eGFR Decline in Later-Stage ADPKD
Reduction in decline in eGFR for patients with later-stage autosomal dominant polycystic kidney disease
ACR: Opioids, SSRIs Tied to Higher Fracture Risk in RA
Increased risk of osteoporotic fracture with selective serotonin reuptake inhibitors, opioids of any strength
ACR: Successful Tapering of DMARDs in RA Explored
Low level of serum CRP at baseline linked to successful down-titration in multivariate analysis
PARP Inhibitors Promising Beyond BRCA1/2 Altered Tumors
Talazoparib caused regression in 5 patient-derived xenografts, 4 without germline BRCA1/2 mutations
