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For patients with previously untreated clear-cell advanced renal-cell carcinoma

Nivolumab Plus Ipilimumab Tops Sunitinib for Advanced Renal CA

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Overall survival, objective response higher than sunitinib for untreated clear-cell advanced RCC
For patients with secondary progressive multiple sclerosis

Siponimod Cuts Risk of Disability Progression in Multiple Sclerosis

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Reduction in 3-month confirmed disability progression in secondary progressive multiple sclerosis
Dipeptidyl peptidase-4 inhibitors are associated with increased risk of inflammatory bowel disease among patients with type 2 diabetes

Dipeptidyl Peptidase-4 Inhibitors in T2DM Linked to IBD

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Higher risk of inflammatory bowel disease with longer use of dipeptidyl peptidase-4 inhibitor
Despite the popularity

Unique Risks Associated With Texting Medical Orders

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Institute of Safe Medication Practices indicates risks such as abbreviations, autocorrection
For patients with persistent asthma

Adjuvant Long-Acting Muscarinic Antagonist Improves Asthma

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Versus adjuvant placebo, LAMA or LABA plus inhaled corticosteroids lowers risk of asthma exacerbations
Use of a low-dose triple combination therapy is effective for rapidly achieving blood pressure control among patients with hypertension

ACC: Low-Dose Triple Combo Pill Effective for Rapid BP Control

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Greater chance of achieving blood pressure target level with combo pill strategy versus usual care
Drug copayments frequently exceed prescription drug costs

Drug Copayments Often Exceed Prescription Drug Costs

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Overpayments affect 23 percent of all prescriptions; more common with generic drugs
The majority of Canadian physical therapists positively view a new interprofessional model of care with pharmacists

PTs Support Interprofessional Model of Care With Pharmacists

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Most survey respondents reported a positive perception of interactions with pharmacists
For patients with gout and cardiovascular disease

ACC: Febuxostat Noninferior to Allopurinol for Gout, CVD

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Noninferior for rates of adverse cardiovascular events; tied to higher all-cause, cardiovascular mortality
The National Comprehensive Cancer Network often makes recommendations for new molecular entities beyond the indications approved by the U.S. Food and Drug Administration

NCCN Recommends New Drugs Beyond FDA-Approved Indications

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NCCN recommended 47 FDA-approved drugs for 113 indications; 39 percent were extra recommendations