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Tag: Prescription Drugs

Most people in the United States are unaware of national cancer drug shortages

Most Patients Are Unaware of Drug Cancer Shortages

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Majority say they want to know about even minor consequences of cancer drug substitutions
Sirolimus may be beneficial for patients with diffuse idiopathic pulmonary neuroendocrine cell hyperplasia

Sirolimus May Be Beneficial in DIPNECH Syndrome

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Beneficial effects seen for three women with diffuse idiopathic pulmonary neuroendocrine cell hyperplasia
Myocarditis in patients treated with immune checkpoint inhibitors may be more common than previously thought

Myocarditis Rare Side Effect of Immune Checkpoint Inhibitors

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Myocarditis with ICIs may be more common than initially thought; responds to higher steroid dosages
Children of first-cousin consanguineous parents are more likely to be in receipt of antidepressant or anxiolytic medications and antipsychotic medications

Mood Disorders Up for Children of Consanguineous Parents

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Increased odds of mental health issues and needing antidepressant, anxiolytic, antipsychotic medications
There is considerable variation in the quality of free-text patient directions in electronic prescriptions

Variations Identified in Free-Text Directions in E-Prescriptions

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However, more than half of all prescriber's patient directions could be categorized into 25 concepts
Using CYP2C19 genotype-guided dual antiplatelet therapy selection is feasible in a real-world setting

Genotype-Guided Antiplatelet Therapy Feasible, Effective

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Genotype-guided therapy improves outcomes among CYP2C19 intermediate, poor metabolizers
Outcomes-based pricing does not reduce the costs of proprotein convertase subtilisin/kexin type 9 inhibitors

Outcomes-Based Pricing Doesn’t Cut Costs of PCSK9 Inhibitors

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Incremental cost-effectiveness ratio for PCSK9 inhibitor improved marginally in three refund scenarios
For castration-resistant prostate cancer

Low-Dose Abiraterone Acetate Noninferior for Prostate Cancer

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Low-dose AA with low-fat breakfast had greater effect on PSA; similar effect to standard dose
Exposure to sodium valproate or a combination of antiepileptic drugs in utero is associated with worse attainment on national educational tests for 7-year-olds

Educational Attainment Down With In Utero Exposure to AEDs

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Exposure to sodium valproate, combo of antiepileptic drugs tied to worse attainment on national tests
Intravitreal anti-vascular endothelial growth factor treatment is not associated with increased risk of systemic adverse events for patients with neovascular age-related macular degeneration

Intravitreal Anti-VEGF Use Not Tied to Systemic Adverse Events

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Risk not up in neovascular age-related macular degeneration, diabetic macular edema