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New opioid prescriptions for U.S. adults using benzodiazepines stopped increasing in 2010

Adults Using Benzodiazepines More Likely to Receive Opioid Rx

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Increase in new opioid prescriptions for U.S. adults using benzodiazepines stopped in 2010
Cancer survivors are more likely to be prescribed five or more unique medications

Polypharmacy More Likely for Cancer Survivors

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More cancer survivors prescribed five or more unique medications, including those with abuse potential
For patients with human epidermal growth factor receptor 2/neu-positive uterine serous carcinoma

New Drug Combo Ups Survival in HER2/neu Uterine Serous Cancer

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Adding intravenous trastuzumab to carboplatin-paclitaxel increased progression-free survival
For patients with chronic obstructive pulmonary disease

Triple Therapy Tied to Reduced Rate of COPD Exacerbations

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Benefits seen for triple therapy with fluticasone furoate, umeclidinium, and vilanterol
Use of short-acting calcium channel blockers is associated with increased risk of pancreatic cancer in postmenopausal women

Calcium Channel Blockers May Up Pancreatic Cancer Risk in Women

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Increased hazard ratios for pancreatic cancer among postmenopausal users of short-acting CCBs
The estimated annual cost of drug-related morbidity and mortality resulting from nonoptimized medication therapy is more than half a trillion dollars in the United States

Nonoptimized Drug Therapy Costs More Than $500 Billion Annually

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After initial Rx use, average cost of individual having treatment failure, new medical problem over $2,000
Pembrolizumab is associated with significantly longer recurrence-free survival than placebo as adjuvant therapy for high-risk stage III melanoma

Adjuvant Pembrolizumab Beneficial in Stage III Melanoma

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Pembrolizumab linked to significantly longer recurrence-free survival at 15-month follow-up
For patients with breast cancer

Endocrine Therapy-Induced Alopecia Seen in Breast Cancer

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92 percent had grade 1 severity alopecia with endocrine tx; pattern similar to androgenetic alopecia
Physicians receiving general payments from pharmaceutical companies are more likely to prescribe their drugs

Odds of Prescribing Drugs Up With Doc Receipt of Payments

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Doctors who receive general payment for cancer drug more likely to prescribe drug marketed by company
Polypharmacy is associated with poorer cognitive and physical capability even after adjustment for disease burden

Polypharmacy Linked to Poorer Cognitive, Physical Capability

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Stronger negative associations for participants with polypharmacy at age 60 to 64 years and at 69 years