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For persons living with HIV in Uganda

Efavirenz Doesn’t Up Depression, Suicidal Ideation in HIV-Infected

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No increased risk of depression or suicidal ideation among persons living with HIV in Uganda
For patients with Parkinson's disease

Parkinson’s Medications Tied to Impulse Control Disorders

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Impulse control disorders strongly associated with dopamine agonist use
Over the past two decades

Many Drugs Made Available Via FDA Expanded Access Programs

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Half of meds ID'd in expanded access programs treat cancer; others for metabolic, endocrine diseases
Dexmedetomidine prevents excessive γ-aminobutyric acid type A receptor function after anesthesia

Dexmedetomidine Cuts γ-Aminobutyric Acid Receptor Function

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Cuts etomidate-induced increase in α5 γ-aminobutyric acid type A receptor cell-surface expression
Ambulatory medication reconciliation is associated with lower risk of a composite primary outcome of combined frequency of emergency department visits and hospitalizations over six months

Diabetes Meds Reconciliation May Reduce Risk of ER Visits

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Medication reconciliation linked to lower risk of combined ER visits, hospitalization over six months
The estimated prevalence of using medications with depression as an adverse effect is 37.2 percent

Meds With Depression As Adverse Side Effect Commonly Used

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Prevalence of depression higher for adults reporting use of multiple meds with depression as side effect
Topical rapamycin seems effective for tuberous sclerosis complex-related facial angiofibromas

Topical Rapamycin Effective for TSC-Related Facial Angiofibromas

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One percent rapamycin seems most effective for tuberous sclerosis complex-linked angiofibromas
Mifepristone pretreatment improves medical management of early pregnancy loss

Mifepristone Pre-Tx Improves Management of Early Miscarriage

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Successful management likely for pretreatment with mifepristone followed by misoprostol
A recall of the opioid overdose antidote Naloxone was announced Monday. The U.S. Food and Drug Administration said the recall was triggered by the possibility of "loose particulate matter on the syringe plunger" that could pose a number of health risks

FDA: Opioid Antidote Naloxone Recalled

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Two lots of Naloxone recalled due to potential presence of particulate matter in syringe plunger
For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer

ASCO: Pembrolizumab Superior for Initial Tx of Advanced NSCLC

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Improved overall survival versus chemotherapy regardless of the PD-L1 tumor proportion score