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For patients with hereditary transthyretin amyloidosis with polyneuropathy

Patisiran, Inotersen Aid Hereditary Transthyretin Amyloidosis

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Improvement in modified Neuropathy Impairment Score+7, Norfolk QoL Diabetic Nephropathy score
Compared to treatment with an inhaled glucocorticoid alone

Combination of LABA + Inhaled Glucocorticoid Safe in Asthma

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Also results in significantly fewer asthma exacerbations than inhaled glucocorticoid alone
Pediatric exposure to buprenorphine can result in serious adverse outcomes

Poison Control Center Data Detail Peds Exposure to Buprenorphine

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Children aged <6 have greater odds of hospital admission than teens with single-substance exposure
At the annual meeting of the American Medical Association

AMA: Docs Declare Drug Shortages Public Health Emergency

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AMA calls for greater manufacturer transparency in order to prepare for disasters, mitigate shortages
For persons living with HIV in Uganda

Efavirenz Doesn’t Up Depression, Suicidal Ideation in HIV-Infected

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No increased risk of depression or suicidal ideation among persons living with HIV in Uganda
For patients with Parkinson's disease

Parkinson’s Medications Tied to Impulse Control Disorders

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Impulse control disorders strongly associated with dopamine agonist use
Over the past two decades

Many Drugs Made Available Via FDA Expanded Access Programs

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Half of meds ID'd in expanded access programs treat cancer; others for metabolic, endocrine diseases
Dexmedetomidine prevents excessive γ-aminobutyric acid type A receptor function after anesthesia

Dexmedetomidine Cuts γ-Aminobutyric Acid Receptor Function

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Cuts etomidate-induced increase in α5 γ-aminobutyric acid type A receptor cell-surface expression
Ambulatory medication reconciliation is associated with lower risk of a composite primary outcome of combined frequency of emergency department visits and hospitalizations over six months

Diabetes Meds Reconciliation May Reduce Risk of ER Visits

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Medication reconciliation linked to lower risk of combined ER visits, hospitalization over six months
The estimated prevalence of using medications with depression as an adverse effect is 37.2 percent

Meds With Depression As Adverse Side Effect Commonly Used

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Prevalence of depression higher for adults reporting use of multiple meds with depression as side effect