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Tag: Prescription Drugs

For relapsing-remitting multiple sclerosis

Risk for Conversion of MS Varies With Different Therapies

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Lower risk for conversion for initial treatment with fingolimod, alemtuzumab, or natalizumab
The U.S. Preventive Services Task Force recommends risk-reducing medications for women at high risk for breast cancer who are at low risk for adverse events

USPSTF Recommends Risk-Reducing Meds for Breast Cancer

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Risk-reducing medications recommended for women at high risk, not for routine use
The median overall survival from diagnosis for patients with stage IV anaplastic lymphoma kinase-positive non-small cell lung cancer is 6.8 years

Median Survival for Stage 4 ALK-Positive NSCLC Nearly 7 Years

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Most patients in study received crizotinib; prognosis worse when more organs have tumors at diagnosis
Three classes of drugs hold potential as repurposed agents to treat patients with serious mental illness

Drug Repurposing May Provide More Psychiatric Tx Options

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Three drug classes tied to lower rates of self-harm and psychiatric stays with serious mental illness
The costs of oral and injectable brand-name drugs increased from 2008 to 2016

Increase in Brand-Name Drug Cost Mainly Due to Existing Drugs

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Rising costs of oral, injectable generic and specialty drugs mostly driven by new product entry
Treating high blood pressure is not associated with an increased fall risk among older women

No Increased Fall Risk With HTN Treatment in Older Women

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Lower incidence rate ratios found for women with treated controlled hypertension, treated uncontrolled HTN
Exercise can consistently yield reductions in blood pressure

Exercise Can Consistently Lower Blood Pressure

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Reductions in BP from exercise comparable but not as great as from medications
For women with provoked vulvodynia

Gabapentin Improves Sexual Function in Provoked Vulvodynia

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Sexual function improved for gabapentin vs. placebo, but still lower than among matched pain-free controls
An approach involving a combination of provider report and pharmacy refill data can improve identification of medication nonadherence among youth with chronic kidney disease

Multimethod Approach Improves ID of Med Nonadherence

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Use of provider report, medication possession ratio improved ID of nonadherence in youth with CKD
For patients with secondary progressive multiple sclerosis

Rituximab Beneficial in Secondary Progressive MS

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Treatment with rituximab linked to lower Expanded Disability Status Scale score, delayed progression