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The compendia used by Medicare for making coverage determinations are inadequate for dermatologic illnesses

Off-Label Uses in Dermatology Often Missing From Compendia

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Only 30.7 percent of 238 treatments used to treat 22 dermatologic conditions listed in compendia
For patients with atrial fibrillation

NOACs Recommended as First-Line Prevention of Stroke in A-Fib

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Updated guidelines also emphasize weight loss for overweight, obese patients with atrial fibrillation
For relapsing-remitting multiple sclerosis

Risk for Conversion of MS Varies With Different Therapies

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Lower risk for conversion for initial treatment with fingolimod, alemtuzumab, or natalizumab
Outpatient benzodiazepine use increased from 2003 to 2015

2003 to 2015 Saw Increase in Outpatient Benzodiazepine Use

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Fourfold increase seen in rate of coprescribing with opioids; twofold increase with other sedating meds
For patients with early Parkinson disease

Levodopa + Carbidopa Does Not Modify Disease in Early Parkinson

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Findings in patients with early Parkinson disease evaluated over the course of 80 weeks
Concurrent use of benzodiazepine receptor modulators and opioids and of nonselective and selective benzodiazepine receptor modulators increased from 1999-2000 to 2013-2014

Benzodiazepine, Opioid Co-Usage Up in the United States

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Increases also noted in co-use of nonselective and selective benzodiazepine receptor modulators
Use of the oral hepatoselective glucokinase activator TTP399 for type 2 diabetes does not cause hypoglycemia and has no detrimental effect on plasma lipids or liver enzymes

Oral Hepatoselective Glucokinase Activator Promising in T2DM

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Clinically significant and sustained reduction in glycated hemoglobin was observed with TTP399
A U.S. Food and Drug Administration advisory panel vote on whether to recommend approval of the first oral medication for type 1 diabetes ended in an 8-8 tie Thursday.

FDA Panel Has Tie Vote on New Type 1 Diabetes Drug

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Zynquista is a once-daily pill meant to help type 1 diabetes patients manage their blood glucose levels
From 2007 to 2016

Medication Treatment for Substance Abuse Up in Facilities

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2007 to 2016 saw increase in use of medication treatment, reaching 36.1 percent in 2016
Ertugliflozin appears safe and effective at improving long-term glycemic control among adults with type 2 diabetes mellitus inadequately controlled on metformin

Ertugliflozin Seems Safe, Effective for Type 2 Diabetes Treatment

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Improvements seen in HbA1c, fasting glucose, body weight, blood pressure over two years