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A pharmacist-led intervention has the potential to reduce prescriptions for inappropriate medication in older adults

Pharmacist-Led Effort Cuts Inappropriate Rx in Older Adults

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Intervention included educational deprescribing information to patients, physicians
Denosumab

Denosumab Promising for TDT-Induced Osteoporosis Treatment

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Higher percentage increase of L1 to L4 and wrist bone mineral density with DMN, reduction in pain
Treatment with dapagliflozin is noninferior to placebo for major adverse cardiovascular events among patients with type 2 diabetes with or at risk for atherosclerotic cardiovascular disease

AHA: Dapagliflozin Noninferior to Placebo for MACE in T2DM

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Treatment resulted in lower HF hospitalization rate in patients with, without atherosclerosis
Icosapent ethyl is associated with a reduced risk for ischemic events among patients with elevated triglyceride levels despite taking statins

AHA: Icosapent Ethyl Cuts CV Risk From Elevated Triglycerides

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Ischemic events reduced among patients with elevated triglycerides despite taking statins
For premenopausal women with stage I to IIIA estrogen receptor-negative

Improved Long-Term Pregnancy Outcomes for Goserelin + Chemo

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Findings seen in premenopausal women with stage I to IIIA hormone receptor-negative breast cancer
Oral zoliflodacin

Zoliflodacin Seems Effective for Some Gonococcal Infections

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In phase 2 trial, oral dose treats urogenital, rectal infections; lower efficacy for pharyngeal infections
An adjunctive buprenorphine/samidorphan combination seems beneficial for patients with major depressive disorder with inadequate response to antidepressant therapy

Buprenorphine/Samidorphan Helpful in Refractory Depression

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Consistently greater reduction in MADRS score from baseline seen for BUP/SAM versus placebo
Prenatal exposure to most medications affecting neurotransmitter systems is not associated with estimates of autism spectrum disorder risk

Most Meds Affecting Neurotransmitters Not Linked to Autism Risk

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Prenatal exposure to 5 groups of meds had nominally significant links to ASD
Intensive blood pressure control and fenofibrate use in patients with type 2 diabetes who are at high risk for cardiovascular disease may increase the risk for adverse kidney events

ASN: Aggressive Control of BP, Lipids in T2DM May Up Kidney Risk

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Strict BP control, fenofibrate use may increase long-term risk for adverse kidney events in T2DM patients
Another hypertension drug is being recalled due to contamination that could pose a cancer risk

Second Hypertension Drug Recalled Due to Contamination

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Some lots of irbesartan being recalled due to contamination with suspected carcinogen