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The reversal agent

ASA: Reversal Agent Cuts Severe Bleeding With Factor Xa Inhibitors

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Bolus plus two-hour infusion of andexanet alfa cuts antifactor Xa activity by 92 percent
In a drug industry first

Johnson & Johnson to Provide Drug Prices in TV Ads

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Drug list prices, typical out-of-pocket costs will appear on screen at end of commercials
Lumacaftor/ivacaftor treatment is generally safe and well tolerated for children aged 2 to 5 years with cystic fibrosis homozygous for the F508del-CFTR mutation

Drug Combo Tolerated in Younger Children With Cystic Fibrosis

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Lumacaftor/ivacaftor safe in children ages 2 to 5 with cystic fibrosis homozygous for F508del-CFTR
Treatment of psoriasis with biologic therapy is associated with a reduction in noncalcified coronary plaque and improved plaque morphology

Psoriasis Tx Linked to Drop in Noncalcified Coronary Plaque

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Noncalcified plaque burden and necrotic core reduced in association with biologic therapy
The clinical benefits of tofacitinib in combination with methotrexate are sustained over two years among patients with rheumatoid arthritis

Tofacitinib Benefits Sustained for Two Years in Patients With RA

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Safety, tolerability through 24 months was consistent with 12-month tofacitinib analysis
A pharmacist-led

Pharmacist-Led Phone Follow-Up May Cut Readmission Rates

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Intervention for polypharmacy patients linked to improved readmission rates, time to readmission
Discontinuing tumor necrosis factor inhibitors before gestational week 20 in women with well-controlled rheumatoid arthritis or juvenile idiopathic arthritis is not associated with disease worsening in late pregnancy

Discontinuing TNFi Before Gestational Week 20 Is Feasible

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No clinically meaningful disease worsening among women with well-controlled RA, juvenile arthritis
A shortage of the anti-anxiety drug buspirone in the United States has patients and doctors concerned.

Shortage of Anxiety Drug Creates Alarm Among Patients, Doctors

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Buspirone price has fallen so low that many manufacturers claim they cannot make a profit on it
Methotrexate is well tolerated and effective for psoriasis in a Chinese population and is more effective for those without psoriatic arthritis

Methotrexate Well Tolerated, Effective for Psoriasis in Chinese

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Greater therapeutic response, fewer adverse events seen in those without psoriatic arthritis
The compendia used by Medicare for making coverage determinations are inadequate for dermatologic illnesses

Off-Label Uses in Dermatology Often Missing From Compendia

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Only 30.7 percent of 238 treatments used to treat 22 dermatologic conditions listed in compendia