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An iterative

Multidimensional Approach Cuts Unneeded Drug-Drug Interaction Alerts

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Number of interruptive DDI alerts substantially decreased as result of alert refinement efforts
For patients with acne

AAD: Isotretinoin Exposure for Acne Not Linked to Depression Risk

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Acne patients with, without isotretinoin exposure had no significant difference in depression frequency
A large Canadian drug distributor sells unapproved and mislabeled medicines to Americans

FDA Warns Americans Not to Buy Drugs From Canadian Company

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CanaRx sells prescription medicines at a lower cost to U.S. public, private employer programs
A safety clinical trial has revealed that tofacitinib (Xeljanz

FDA: Pulmonary Embolism Risk Up With Tofacitinib 10 mg for RA

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Safety clinical trial shows risk for PE, death with 10-mg dose versus 5-mg dose, TNF inhibitor
For patients with advanced Merkel cell carcinoma

Tumor Control Durable With Pembrolizumab in Merkel Cell Cancer

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28 of 50 advanced MCC patients responded; 24-month overall survival rate was 68.7 percent
Fluoroquinolone stewardship interventions at hospitals are associated with less fluoroquinolone prescribing during hospitalization but not at discharge

Stewardship Programs Decrease Inpatient Fluoroquinolone Rx

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Interventions tied to less prescribing in hospital but did not impact fluoroquinolone discharge treatment
Candesartan plus hydrochlorothiazide

Lowering BP, Lipids in Healthy Elderly Has No Cognitive Effect

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Candesartan/hydrochlorothiazide, rosuvastatin, combination therapy do not affect cognitive decline
The battle against new HIV infections has lost some steam in recent years

CDC: Progress in HIV Prevention Has Stalled in the United States

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Agency says effective HIV prevention, treatment not reaching those who could most benefit
The demand for naloxone is relatively inelastic with respect to changes in its out-of-pocket price

Converting Naloxone to OTC Expected to Increase Sales

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Demand for naloxone is inelastic, with 1 percent increase in price resulting in 0.27 percent drop in sales
For patients with coronary artery disease

Odds of Receiving Tx for CAD Up With Medicare Advantage

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However, no significant difference seen in intermediate outcomes for those enrolled in MA, FFS Medicare