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Atrasentan is associated with a reduced risk for renal events in patients with type 2 diabetes and chronic kidney disease

Atrasentan Tied to Lower Risk for Kidney Events in T2DM With CKD

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Reduced risk seen for primary composite renal end point event; more frequent fluid retention, anemia reported
Monotherapy with UB-421 antibody

UB-421 Monotherapy Maintains HIV Viral Suppression

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Suppression maintained for up to 16 weeks in HIV-infected undergoing analytic treatment interruption
The overall burden of outpatient parenteral antimicrobial therapy is substantially higher than that of oral therapy for caregivers of children on prolonged antimicrobial therapy after hospital discharge

Parenteral Antimicrobial Tx at Home Burdens Children’s Caregivers

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Compared with those who receive oral therapy, caregivers miss more work, have lower QoL scores
For patients with chronic myeloid leukemia

Reasons for TKI Discontinuation ID’d in Chronic Myeloid Leukemia

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Treatment-free remission maintained in 14 of 21 patients who discontinued tyrosine kinase inhibitors
Antiepileptic drug use may increase the risk for pneumonia in patients with Alzheimer disease

AEDs Tied to Higher Pneumonia Risk in Alzheimer Patients

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Risk for pneumonia highest within first month of antiepileptic drug use but persists through two years
Canagliflozin is associated with a reduced risk for renal and cardiovascular events for patients with type 2 diabetes and kidney disease

Canagliflozin Seems Effective for Patients With T2DM, Kidney Disease

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Reductions seen in risk for kidney failure, cardiovascular disease with canagliflozin versus placebo
Medication shortages are frequently reported by pharmacy practice managers

Pharmacy Practice Managers Report Frequent Drug Shortages

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More than one-third of respondents reported no administrative methods for responding to shortages
Peripheral nerve blockade with regular local anesthetic and liposomal bupivacaine is associated with lower oral morphine equivalent use at 72 hours after major lower extremity amputation

Peripheral Nerve Block May Cut Opioid Use After Amputation

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Peripheral nerve block helps improve pain control after major lower extremity amputation
Use of the orally administered β-site amyloid precursor protein-cleaving enzyme 1 inhibitors

Verubecestat, Atabecestat Not Beneficial for Preventing Alzheimer Disease

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Two trials show lack of effectiveness versus placebo for preclinical Alzheimer disease
For people with hepatitis C virus who inject drugs and receive opioid agonist therapy

High Response Seen for All Hep C Tx Models in Injection Drug Users

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Directly observed therapy tied to greater adherence than self-administered individual treatment