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Community-dwelling patients with Alzheimer disease experience a lower risk for fractures

Thiazide Use May Lower Fracture Risk in Patients With Alzheimer Disease

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Longer thiazide use tied to decreased risk for low-energy fractures, hip fractures in Alzheimer disease
The addition of liraglutide to metformin is effective and safe for children and adolescents with type 2 diabetes

Liraglutide Added to Metformin Effective for Type 2 Diabetes

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Trial shows superiority of liraglutide with respect to glycemic control in children, adolescents
The risk for adverse drug reactions may be higher for women

Gender Differences Seen in Adverse Drug Reactions

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Differences found in reaction symptoms and types of drugs tied to adverse reactions
In patients with type 1 diabetes

Dapagliflozin Improves Glucose Outcomes in Type 1 Diabetes

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Benefits observed without increase in time spent in hypoglycemic range
Naproxen sodium twice daily is not associated with reduced progression of presymptomatic Alzheimer disease among cognitively intact people at risk for the condition

Naproxen Sodium Does Not Slow Presymptomatic Alzheimer Disease

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Study shows increased frequency of adverse events but little impact on rate of change in APS
Consumption of sleeping pills is linked to a subsequent increase in the number of antihypertensive drugs taken among older adults

Sleeping Pill Use Tied to Greater Need for BP Meds in Older Adults

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But no association observed between sleep duration or quality and change in BP drug use
Long-term osteoporosis drug therapy reduces fracture risk in women but may increase risk for rare adverse events

Risks, Benefits of Long-Term Drug Therapy for Osteoporosis Reviewed

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Position paper outlines research gaps for clinical management of long-term osteoporosis drug therapy
Metformin is associated with long-term weight loss

Metformin May Help Obese With Prediabetes Maintain Weight Loss

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Results seen in post hoc analysis performed in Diabetes Prevention Program Outcomes Study
Slow-release implantable naltrexone is associated with better outcomes than the oral drug for HIV-positive patients with an opioid addiction

Naltrexone Implant Helps HIV Patients Prevent Opioid Relapse

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Compared with oral naltrexone, implant also improved HIV outcomes among those with opioid dependence
Men receiving 5α-reductase inhibitors have an increased risk for new-onset type 2 diabetes mellitus

Risk for T2DM Increased With Use of 5α-Reductase Inhibitors

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Increased risk seen among men using dutasteride, finasteride for benign prostatic hyperplasia