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Spending associated with essential medicines grew substantially from 2011 to 2015 for Medicare Part D beneficiaries

Medicare Spending on Essential Medicines Up 116 Percent From 2011 to 2015

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22 percent of increased total spending due to higher per-unit cost of existing drugs
For women with intrahepatic cholestasis of pregnancy

Common Therapy for Obstetric Cholestasis Found Ineffective

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Treatment with ursodeoxycholic acid versus placebo yielded no significant difference in outcome
Sotagliflozin

Addition of Sotagliflozin for T1DM Alters Renal Hemodynamics

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Addition of SOTA tied to reductions in estimated glomerular filtration rate, blood pressure
From 2012 to 2018

2012 to 2018 Saw Substantial Rise in Naloxone Dispensing

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Regional variation in naloxone dispensing considerable; rates lowest in most rural counties
Efpeglenatide once weekly leads to dose-dependent reductions in glucose and body weight in patients with early type 2 diabetes

Study Explores Dose Ranges for Efpeglenatide in Early T2DM

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Safety profile consistent with other long-acting glucagon-like peptide 1 receptor agonists
Brand-brand competition in the U.S. pharmaceutical market has not lowered drug list prices

Brand-Brand Competition Has Not Cut Prices in Pharma Market

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Review shows evidence that brand-brand competition was mediated by quality of competing drugs
For adolescents with perinatally acquired HIV

Compliance With Meds Falters With Age in Youth Born With HIV

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Prevalence of nonadherence increased from preadolescence to late adolescence/young adulthood
For patients with previously untreated chronic lymphocytic leukemia

Ibrutinib-Rituximab Beats Chemoimmunotherapy for CLL

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Progression-free, overall survival improved in the ibrutinib-rituximab group at three years
Americans could import less expensive prescription drugs from Canada under a plan being developed by the Trump administration.

Trump Admin Announces Plan to Allow Drug Imports From Canada

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Plan will start by exploring options for importing certain prescription drugs to lower costs for Americans
Compared with placebo

Oral Semaglutide Reduces HbA1c, Weight in Patients With T2DM

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Semaglutide has a safety and tolerability profile consistent with other GLP-1 receptor agonists